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8SBG

Crystal structure of B. theta tryptophanase in holo form

Summary for 8SBG
Entry DOI10.2210/pdb8sbg/pdb
DescriptorTryptophanase, PYRIDOXAL-5'-PHOSPHATE (3 entities in total)
Functional Keywordsplp-dependent enzyme, tryptophanase, tryptophan-indole lyase, lyase
Biological sourceBacteroides thetaiotaomicron
Total number of polymer chains1
Total formula weight54833.82
Authors
Graboski, A.L.,Redinbo, M.R. (deposition date: 2023-04-03, release date: 2023-08-23, Last modification date: 2023-11-29)
Primary citationGraboski, A.L.,Kowalewski, M.E.,Simpson, J.B.,Cao, X.,Ha, M.,Zhang, J.,Walton, W.G.,Flaherty, D.P.,Redinbo, M.R.
Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate.
Cell Chem Biol, 30:1402-1413.e7, 2023
Cited by
PubMed: 37633277
DOI: 10.1016/j.chembiol.2023.07.015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.94 Å)
Structure validation

221051

건을2024-06-12부터공개중

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