8SAH
Huntingtin C-HEAT domain in complex with HAP40
Summary for 8SAH
Entry DOI | 10.2210/pdb8sah/pdb |
EMDB information | 28766 |
Descriptor | Huntingtin, 40-kDa huntingtin-associated protein (2 entities in total) |
Functional Keywords | huntingtin, scaffold, heat repeats, structural genomics, structural genomics consortium, sgc, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 158822.01 |
Authors | Harding, R.J.,Deme, J.C.,Alteen, M.G.,Arrowsmith, C.H.,Lea, S.M.,Structural Genomics Consortium (SGC) (deposition date: 2023-03-31, release date: 2023-04-26, Last modification date: 2023-09-20) |
Primary citation | Alteen, M.G.,Deme, J.C.,Alvarez, C.P.,Loppnau, P.,Hutchinson, A.,Seitova, A.,Chandrasekaran, R.,Silva Ramos, E.,Secker, C.,Alqazzaz, M.,Wanker, E.E.,Lea, S.M.,Arrowsmith, C.H.,Harding, R.J. Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40. Structure, 31:1121-1131.e6, 2023 Cited by PubMed: 37390814DOI: 10.1016/j.str.2023.06.002 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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