8S8O

Solution Structure of cAMP-dependent Protein Kinase RII-alpha Subunit Dimerization and Docking Domain Complex with Microtubule Associated Protein 2c (84-111)

Summary for 8S8O

Entry DOI	10.2210/pdb8s8o/pdb
Descriptor	cAMP-dependent protein kinase type II-alpha regulatory subunit, Isoform 3 of Microtubule-associated protein 2 (2 entities in total)
Functional Keywords	akap, pka, map2c, idp, protein-protein complex, 4-helix bundle, microtubule, protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	14594.58
Authors	Bartosik, V.,Lanikova, A.,Janackova, Z.,Padrta, P.,Zidek, L. (deposition date: 2024-03-06, release date: 2024-09-25)
Primary citation	Bartosik, V.,Plucarova, J.,Lanikova, A.,Janackova, Z.,Padrta, P.,Jansen, S.,Varecka, V.,Gruber, T.,Feller, S.M.,Zidek, L. Structural basis of binding the unique N-terminal domain of microtubule-associated protein 2c to proteins regulating kinases of signaling pathways. J.Biol.Chem., 300:107551-107551, 2024 Cited by PubMed: 39002671 DOI: 10.1016/j.jbc.2024.107551 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation