8S8A
Human pyridoxal phosphatase in complex with 7,8-dihydroxyflavone without phosphate
Summary for 8S8A
Entry DOI | 10.2210/pdb8s8a/pdb |
Descriptor | Chronophin, 7,8-bis(oxidanyl)-2-phenyl-chromen-4-one, FORMIC ACID, ... (6 entities in total) |
Functional Keywords | inhibitor, pdxp, 7 8-dihydroxyflavone, flavone, chronophin, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 32098.17 |
Authors | Brenner, M.,Gohla, A.,Schindelin, H. (deposition date: 2024-03-06, release date: 2024-06-12, Last modification date: 2024-06-26) |
Primary citation | Brenner, M.,Zink, C.,Witzinger, L.,Keller, A.,Hadamek, K.,Bothe, S.,Neuenschwander, M.,Villmann, C.,von Kries, J.P.,Schindelin, H.,Jeanclos, E.,Gohla, A. 7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase. Elife, 13:-, 2024 Cited by PubMed: 38856179DOI: 10.7554/eLife.93094 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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