8S76

Soluble epoxide hydrolase in complex with PROTAC JSF67

This is a non-PDB format compatible entry.

Summary for 8S76

• Entry DOI: 10.2210/pdb8s76/pdb
• Related: 8S75
• Descriptor: Bifunctional epoxide hydrolase 2, ~{N}-[[4-[3-[1-[2-[2-[2-[[2-[2,6-bis(oxidanylidene)piperidin-3-yl]-1,3-bis(oxidanylidene)isoindol-5-yl]amino]-2-oxidanylidene-ethoxy]ethoxy]ethyl]-1,2,3-triazol-4-yl]propylsulfonylamino]-2-(trifluoromethyl)phenyl]methyl]-1-[(3-fluorophenyl)methyl]indole-5-carboxamide, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: complex, structural genomics, structural genomics consortium, sgc, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 86979.30

Authors

Kumar, A.,Schoenfeld, J.,Hiesinger, K.,Lillich, F.,Proschak, E.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2024-02-29, release date: 2025-03-12)

• Primary citation: Kumar, A.,Schoenfeld, J.,Hiesinger, K.,Lillich, F.,Proschak, E.,Knapp, S.,Structural Genomics Consortium (SGC); Soluble epoxide hydrolase in complex with PROTAC JSF67; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.48 Å)