8S73

Crystal structure of Fab-antiCD43 monoclonal antibody complexed to a bis-Tn glycopeptide

Summary for 8S73

• Entry DOI: 10.2210/pdb8s73/pdb
• Descriptor: G2D11(VH-CH1), antiCD43(VL-CL), bis-Tn glycopeptide, ... (6 entities in total)
• Functional Keywords: monoclonal antibodies, fab-anticd43, antigen tn, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 6
• Total formula weight: 95994.47

Authors

Hurtado-Guerrero, R.,Macias-Leon, J. (deposition date: 2024-02-29, release date: 2025-06-25)

• Primary citation: Hurtado-Guerrero, R.,Gatos, S.,Gines-Alcober, I.,Macias-Leon, J.,Manuel Gonzalez-Ramirez, A.,Kasapoglu, I.,Veloz, B.,Companon, I.,Ghirardello, M.,Merino, P.,Corzana, F.,Blixt, O.; Recognizing Tn and STn Epitopes in Protein Context: Structural Advances in Phage Display Libraries for Tumor-Specific Antibody Discovery; Nat.Chem.Biol., 2025

Experimental method

X-RAY DIFFRACTION (2.2 Å)