8S30
Crystal structure of human PLK1 Polo-Box Domain in complex with Mis18
Summary for 8S30
Entry DOI | 10.2210/pdb8s30/pdb |
Descriptor | Serine/threonine-protein kinase PLK1, Protein Mis18-alpha (3 entities in total) |
Functional Keywords | plk1, mis18 complex, centromere, chromosome missegregation, cell cycle |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 28756.71 |
Authors | |
Primary citation | Jeyaprakash, A.A.,Medina-Pritchard, B. PLK1-mediated phosphorylation cascade activates Mis18 complex to ensure centromere inheritance Science, 2024 Cited by DOI: 10.1126/science.ado8270PDB entries with the same primary citation |
Experimental method |
Structure validation
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