8S0T

Cryo-EM structure of CAK in complex with SY-5609

Summary for 8S0T

• Entry DOI: 10.2210/pdb8s0t/pdb
• EMDB information: 19627 19628
• Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... (5 entities in total)
• Functional Keywords: kinase, covalent inhibitor, transcription, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 87809.10

Authors

Feng, J.,Cronin, N.B.,Marineau, J.J.,Greber, B.J. (deposition date: 2024-02-14, release date: 2024-12-25)

• Primary citation: Jones, T.,Feng, J.,Koh, A.F.,Cronin, N.B.,Kotecha, A.,Marineau, J.J.,Greber, B.J.,Taatjes, D.; Cryo-EM structure of CAK in complex with SY-5609; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.3 Å)