8RY2
Crystal Structure of ANV419, a novel IL-2/anti-IL-2 antibody fusion protein
Summary for 8RY2
Entry DOI | 10.2210/pdb8ry2/pdb |
Descriptor | ANV419 heavy-chain, ANV419 light-chain (3 entities in total) |
Functional Keywords | immuno-oncology, cytokine |
Biological source | Homo sapiens More |
Total number of polymer chains | 4 |
Total formula weight | 126496.00 |
Authors | |
Primary citation | Murer, P.,Brannetti, B.,Rondeau, J.M.,Petersen, L.,Egli, N.,Popp, S.,Regnier, C.,Richter, K.,Katopodis, A.,Huber, C. Discovery and development of ANV419, an IL-2/anti-IL-2 antibody fusion protein with potent CD8+ T and natural killer cell-stimulating capacity for cancer immunotherapy. Mabs, 16:2381891-2381891, 2024 Cited by PubMed: 39041287DOI: 10.1080/19420862.2024.2381891 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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