8RWL

Crystal structure of Methanopyrus kandleri malate dehydrogenase mutant 1

Summary for 8RWL

• Entry DOI: 10.2210/pdb8rwl/pdb
• Related: 8RS5
• Descriptor: Malate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (6 entities in total)
• Functional Keywords: malate dehydrogenase, rossmann-like motif, nad(p)h binding site, oxidoreductase
• Biological source: Methanopyrus kandleri
• Total number of polymer chains: 2
• Total formula weight: 71263.23

Authors

Coquille, S.,Roche, J.,Engilberge, S.,Girard, E.,Madern, D. (deposition date: 2024-02-05, release date: 2024-07-10)

• Primary citation: Coquille, S.,Simoes Pereira, C.,Brochier-Armanet, C.,Roche, J.,Santoni, G.,Coquelle, N.,Girard, E.,Sterpone, F.,Madern, D.; Navigating the conformational landscape of an enzyme. Stabilization of a low populated conformer by evolutionary mutations triggers Allostery into a non-allosteric enzyme.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)