8RWL

Crystal structure of Methanopyrus kandleri malate dehydrogenase mutant 1

8RWL の概要

• エントリーDOI: 10.2210/pdb8rwl/pdb
• 関連するPDBエントリー: 8RS5
• 分子名称: Malate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: malate dehydrogenase, rossmann-like motif, nad(p)h binding site, oxidoreductase
• 由来する生物種: Methanopyrus kandleri
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 71263.23

構造登録者

Coquille, S.,Roche, J.,Engilberge, S.,Girard, E.,Madern, D. (登録日: 2024-02-05, 公開日: 2024-07-10)

• 主引用文献: Coquille, S.,Simoes Pereira, C.,Brochier-Armanet, C.,Roche, J.,Santoni, G.,Coquelle, N.,Girard, E.,Sterpone, F.,Madern, D.; Navigating the conformational landscape of an enzyme. Stabilization of a low populated conformer by evolutionary mutations triggers Allostery into a non-allosteric enzyme.; To Be Published,

実験手法

X-RAY DIFFRACTION (2.3 Å)