8RUV

HIF prolyl hydroxylase 2 (PHD2) T387I variant bound to Fe(III), 2-oxoglutarate (2OG) and Hypoxia-inducible Factor 2alpha (HIF2alpha)

Summary for 8RUV

• Entry DOI: 10.2210/pdb8ruv/pdb
• Descriptor: Egl nine homolog 1, Hypoxia-inducible Factor-2alpha, FE (III) ION, ... (5 entities in total)
• Functional Keywords: 2og oxygenase, prolyl hydroxylase, oxygen sensing, hypoxia, oxidoreductase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 27859.38

Authors

Fiorini, G.,Schofield, C.J.,Arif, F.,Kibria, M.M. (deposition date: 2024-01-31, release date: 2025-02-12)

• Primary citation: Fiorini, G.,Schofield, C.J.; Investigating gatekeeper residues in Prolyl hydroxylase 2; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.66 Å)