8RUT
HIF prolyl-hydroxylase-2 (PHD2) T387V variant bound to Fe(III), 2-oxoglutarate (2OG) and Hypoxia-inducible Factor-2alpha (HIF-2alpha)
Summary for 8RUT
| Entry DOI | 10.2210/pdb8rut/pdb |
| Descriptor | Egl nine homolog 1, Hypoxia-inducible Factor-2alpha, ACETATE ION, ... (6 entities in total) |
| Functional Keywords | 2og oxygenase, oxygen sensing, prolyl hydroxylase, substrate complex, oxidoreductase |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 28033.51 |
| Authors | |
| Primary citation | Fiorini, G.,Schofield, C.J. HIF prolyl hydroxylase 2 (PHD2) T387V variant bound to Hypoxia-inducible Factor 2alpha (HIF-2alpha To Be Published, |
| Experimental method | X-RAY DIFFRACTION (1.62 Å) |
Structure validation
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