8RU4

Crystal structure of Human Catenin Beta-1 in complex with stitched peptide inhibitor

Summary for 8RU4

• Entry DOI: 10.2210/pdb8ru4/pdb
• Descriptor: Catenin beta-1, Axin-1, alpha-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: peptidometic inhibitor of catenin beta-1, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 117296.04

Authors

Yeste Vazquez, A.,Klintrot, C.I.R.,Grossmann, T.N.,Hennig, S. (deposition date: 2024-01-30, release date: 2024-09-04)

• Primary citation: Yeste-Vazquez, A.,Paulussen, F.M.,Wendt, M.,Klintrot, R.,Schulte, C.,Wallraven, K.,van Gijzel, L.,Simeonov, B.,van der Gaag, M.,Gerber, A.,Maric, H.M.,Hennig, S.,Grossmann, T.N.; Structure-Based Design of Bicyclic Helical Peptides That Target the Oncogene beta-Catenin.; Angew.Chem.Int.Ed.Engl., :e202411749-e202411749, 2024; PubMed: 39167026; DOI: 10.1002/anie.202411749

Experimental method

X-RAY DIFFRACTION (2.13 Å)