8RU3
Crystal structure of beta-catenin in complex with alpha-helical peptide inhibitor
Summary for 8RU3
Entry DOI | 10.2210/pdb8ru3/pdb |
Descriptor | Catenin beta-1, Axin-1, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | peptidometic inhibitor of catenin beta-1, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 59893.52 |
Authors | Yeste Vazquez, A.,Klintrot, C.I.R.,Grossmann, T.N.,Hennig, S. (deposition date: 2024-01-30, release date: 2024-09-04) |
Primary citation | Yeste-Vazquez, A.,Paulussen, F.M.,Wendt, M.,Klintrot, R.,Schulte, C.,Wallraven, K.,van Gijzel, L.,Simeonov, B.,van der Gaag, M.,Gerber, A.,Maric, H.M.,Hennig, S.,Grossmann, T.N. Structure-Based Design of Bicyclic Helical Peptides That Target the Oncogene beta-Catenin. Angew.Chem.Int.Ed.Engl., :e202411749-e202411749, 2024 Cited by PubMed: 39167026DOI: 10.1002/anie.202411749 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.001 Å) |
Structure validation
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