8RTB
Extended inner membrane complex (IMC) protomer structure (TrwM/VirB3-TrwK/VirB4-TrwI/VirB6-TrwG/VirB8-TrwE/VirB10) from the fully-assembled R388 type IV secretion system determined by cryo-EM.
Summary for 8RTB
| Entry DOI | 10.2210/pdb8rtb/pdb |
| EMDB information | 19485 |
| Descriptor | TrwM protein, TrwK protein, TrwG protein, ... (5 entities in total) |
| Functional Keywords | type iv secretion system type 4 secretion system t4ss inner membrane complex imc imc-protomer extended imc r388 plasmid conjugation bacterial secretion secretion secretion system protein complex virb3 virb4 virb6 virb8 virb10 trwm trwk trwi trwg trwe, membrane protein |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 9 |
| Total formula weight | 380800.38 |
| Authors | Mace, K.,Waksman, G. (deposition date: 2024-01-25, release date: 2024-06-19, Last modification date: 2024-07-03) |
| Primary citation | Mace, K.,Waksman, G. Cryo-EM structure of a conjugative type IV secretion system suggests a molecular switch regulating pilus biogenesis. Embo J., 2024 Cited by PubMed: 38886579DOI: 10.1038/s44318-024-00135-z PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.83 Å) |
Structure validation
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