8RTB
Extended inner membrane complex (IMC) protomer structure (TrwM/VirB3-TrwK/VirB4-TrwI/VirB6-TrwG/VirB8-TrwE/VirB10) from the fully-assembled R388 type IV secretion system determined by cryo-EM.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | TrwM protein | polymer | 104 | 12292.6 | 1 | UniProt (O50329) Pfam (PF05101) | Escherichia coli | |
| 2 | B, C (A, B) | TrwK protein | polymer | 823 | 93769.9 | 2 | UniProt (O50330) Pfam (PF03135) Pfam (PF19044) | Escherichia coli | |
| 3 | D, E, F, G (E, D, F, G) | TrwG protein | polymer | 231 | 25800.0 | 4 | UniProt (O50335) Pfam (PF04335) | Escherichia coli | |
| 4 | H (H) | TrwE protein | polymer | 395 | 42443.8 | 1 | UniProt (O50337) Pfam (PF03743) | Escherichia coli | |
| 5 | I (J) | TrwI protein | polymer | 342 | 35324.2 | 1 | UniProt (O50333) Pfam (PF04610) | Escherichia coli |
Sequence modifications
C: 1 - 104 (UniProt: O50329)
E, D, F, G: 1 - 231 (UniProt: O50335)
H: 1 - 395 (UniProt: O50337)
J: 1 - 342 (UniProt: O50333)
| PDB | External Database | Details |
|---|---|---|
| Trp 24 | Leu 24 | conflict |
| Val 26 | Glu 26 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 188 | Arg 188 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Asp 335 | Asn 335 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gln 108 | Glu 108 | conflict |
| Leu 152 | Pro 152 | conflict |
| Leu 153 | Ala 153 | conflict |
| Ala 154 | Gly 154 | conflict |
| Thr 155 | Tyr 155 | conflict |
| Leu 157 | Pro 157 | conflict |
| Leu 158 | Ala 158 | conflict |
| Ala 159 | Gly 159 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 380800.4 | |
| All* | Total formula weight | 380800.4 |
