8RSK

Crystal structure of Methanobrevibacter oralis macrodomain in complex with Asn-ADPr

This is a non-PDB format compatible entry.

Summary for 8RSK

• Entry DOI: 10.2210/pdb8rsk/pdb
• Descriptor: O-acetyl-ADP-ribose deacetylase, ZINC ION, (2~{S})-4-[[(2~{S},3~{R},4~{S},5~{R})-5-[[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]amino]-2-azanyl-4-oxidanylidene-butanoic acid, ... (6 entities in total)
• Functional Keywords: adp-ribosylation, adp-ribose, adp-ribosylhydrolase, lipoylation, metalloenzyme, hydrolase
• Biological source: Methanobrevibacter oralis
• Total number of polymer chains: 3
• Total formula weight: 92294.91

Authors

Ariza, A. (deposition date: 2024-01-24, release date: 2024-09-25, Last modification date: 2024-10-02)

• Primary citation: Ariza, A.,Liu, Q.,Cowieson, N.,Ahel, I.,Filippov, D.V.,Rack, J.G.M.; Evolutionary and molecular basis of ADP-ribosylation reversal by zinc-dependent macrodomains.; J.Biol.Chem., :107770-107770, 2024; PubMed: 39270823; DOI: 10.1016/j.jbc.2024.107770

Experimental method

X-RAY DIFFRACTION (2.359 Å)