8RS7

Crystal structure of Zika Virus NS2B-NS3 protease in complex with an allosteric inhibitor

This is a non-PDB format compatible entry.

Summary for 8RS7

• Entry DOI: 10.2210/pdb8rs7/pdb
• Descriptor: Genome polyprotein, 1-[3-[[5-[4-[2-(dimethylamino)ethoxy]-6-methyl-pyrimidin-5-yl]pyridin-2-yl]methyl]-1,2,3-oxadiazol-3-ium-5-yl]-3-[3-(trifluoromethyl)phenyl]urea (3 entities in total)
• Functional Keywords: zika virus, ns2b-ns3 protease, allosteric inhibitor, compound 1, hydrolase
• Biological source: Zika virus
• Total number of polymer chains: 2
• Total formula weight: 49553.26

Authors

Ontoria, J.M.,Torrente, E. (deposition date: 2024-01-24, release date: 2025-11-05, Last modification date: 2025-12-03)

• Primary citation: Ontoria, J.M.,Torrente, E.; Crystal structure of Zika Virus NS2B-NS3 protease in complex with an allosteric inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.18 Å)