8RS0

Structure of RyR1 in detergent in primed state in complex with nanobody and FKBP

This is a non-PDB format compatible entry.

Summary for 8RS0

• Entry DOI: 10.2210/pdb8rs0/pdb
• EMDB information: 19472
• Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, Nanobody 9657, ... (7 entities in total)
• Functional Keywords: ion channel, ca2+, tetramer, transport protein
• Biological source: Vicugna pacos; More
• Total number of polymer chains: 12
• Total formula weight: 2370125.64

Authors

Li, C.,Efremov, R.G. (deposition date: 2024-01-24, release date: 2024-10-09)

• Primary citation: Li, C.,Willegems, K.,Uchanski, T.,Pardon, E.,Steyaert, J.,Efremov, R.G.; Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM.; J.Biol.Chem., :107734-107734, 2024; PubMed: 39233227; DOI: 10.1016/j.jbc.2024.107734

Experimental method

ELECTRON MICROSCOPY (3.3 Å)