8RRX

Structure of RyR1 reconstituted into lipid nanodisc in primed state in complex with Ca2+, ATP, caffeine and Nb9657

This is a non-PDB format compatible entry.

Summary for 8RRX

• Entry DOI: 10.2210/pdb8rrx/pdb
• EMDB information: 19468
• Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, Nanobody 9657, ... (8 entities in total)
• Functional Keywords: ion channel, ca2+, tetramer, transport protein
• Biological source: Vicugna pacos; More
• Total number of polymer chains: 12
• Total formula weight: 2373165.94

Authors

Li, C.,Efremov, R.G. (deposition date: 2024-01-23, release date: 2024-10-09)

• Primary citation: Li, C.,Willegems, K.,Uchanski, T.,Pardon, E.,Steyaert, J.,Efremov, R.G.; Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM.; J.Biol.Chem., :107734-107734, 2024; PubMed: 39233227; DOI: 10.1016/j.jbc.2024.107734

Experimental method

ELECTRON MICROSCOPY (3.1 Å)