8RRS

Structure of mouse RyR2 solubilised in detergent in open state in complex with Ca2+, ATP, caffeine and Nb9657.

This is a non-PDB format compatible entry.

Summary for 8RRS

• Entry DOI: 10.2210/pdb8rrs/pdb
• EMDB information: 19463
• Descriptor: Ryanodine receptor 2, Nanobody 9657, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: ion channel, ca2+, tetramer, transport protein
• Biological source: Vicugna pacos; More
• Total number of polymer chains: 8
• Total formula weight: 2325873.42

Authors

Li, C.,Efremov, R.G. (deposition date: 2024-01-23, release date: 2024-10-09)

• Primary citation: Li, C.,Willegems, K.,Uchanski, T.,Pardon, E.,Steyaert, J.,Efremov, R.G.; Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM.; J.Biol.Chem., :107734-107734, 2024; PubMed: 39233227; DOI: 10.1016/j.jbc.2024.107734

Experimental method

ELECTRON MICROSCOPY (3.4 Å)