8RQ2

Escherichia coli 50S subunit in complex with the antimicrobial peptide Api88 - conformation III

8RQ2 の概要

• エントリーDOI: 10.2210/pdb8rq2/pdb
• EMDBエントリー: 19429
• 分子名称: Large ribosomal subunit protein bL32, Large ribosomal subunit protein uL3, Large ribosomal subunit protein uL4, ... (32 entities in total)
• 機能のキーワード: ribosome, antimicrobial peptide, rna, ribosomal protein, pramp, proline-rich peptide, antibiotics, 50s, api88
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 34
• 化学式量合計: 1351190.19

構造登録者

Lauer, S.,Nikolay, R.,Spahn, C. (登録日: 2024-01-17, 公開日: 2024-05-22)

• 主引用文献: Lauer, S.M.,Reepmeyer, M.,Berendes, O.,Klepacki, D.,Gasse, J.,Gabrielli, S.,Grubmuller, H.,Bock, L.V.,Krizsan, A.,Nikolay, R.,Spahn, C.M.T.,Hoffmann, R.; Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88.; Nat Commun, 15:3945-3945, 2024; PubMed: 38730238; DOI: 10.1038/s41467-024-48027-4

実験手法

ELECTRON MICROSCOPY (2.44 Å)