8ROL

Human cohesin SMC3-HD(EQ)/RAD21-N complex - ATP-Mg-bound conformation - Form 2

Summary for 8ROL

• Entry DOI: 10.2210/pdb8rol/pdb
• Descriptor: Structural maintenance of chromosomes protein 3, Double-strand-break repair protein rad21 homolog, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: 3d genome organization, chromatin, cohesin, atpase activity, atpase cycle, nuclear protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 65556.86

Authors

Vitoria Gomes, M.,Romier, C. (deposition date: 2024-01-11, release date: 2024-09-11, Last modification date: 2024-09-25)

• Primary citation: Vitoria Gomes, M.,Landwerlin, P.,Diebold-Durand, M.L.,Shaik, T.B.,Durand, A.,Troesch, E.,Weber, C.,Brillet, K.,Lemee, M.V.,Decroos, C.,Dulac, L.,Antony, P.,Watrin, E.,Ennifar, E.,Golzio, C.,Romier, C.; The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.; Cell Rep, 43:114656-114656, 2024; PubMed: 39240714; DOI: 10.1016/j.celrep.2024.114656

Experimental method

X-RAY DIFFRACTION (3.11 Å)