8ROL
Human cohesin SMC3-HD(EQ)/RAD21-N complex - ATP-Mg-bound conformation - Form 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Structural maintenance of chromosomes protein 3 | polymer | 462 | 52391.4 | 1 | UniProt (Q9UQE7) Pfam (PF02463) | Homo sapiens (human) | SMC protein 3,SMC-3,Basement membrane-associated chondroitin proteoglycan,Bamacan,Chondroitin sulfate proteoglycan 6,Chromosome-associated polypeptide,hCAP |
| 2 | B (B) | Double-strand-break repair protein rad21 homolog | polymer | 110 | 12617.9 | 1 | UniProt (O60216) Pfam (PF04825) | Homo sapiens (human) | hHR21,Nuclear matrix protein 1,NXP-1,SCC1 homolog |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 1 | Chemie (AGS) |
Sequence modifications
A: 1 - 211 (UniProt: Q9UQE7)
A: 979 - 1217 (UniProt: Q9UQE7)
B: 1 - 102 (UniProt: O60216)
A: 979 - 1217 (UniProt: Q9UQE7)
| PDB | External Database | Details |
|---|---|---|
| Gly 967 | - | linker |
| Ser 968 | - | linker |
| Gly 969 | - | linker |
| Ser 970 | - | linker |
| Leu 971 | - | linker |
| Val 972 | - | linker |
| Pro 973 | - | linker |
| Arg 974 | - | linker |
| Gly 975 | - | linker |
| Ser 976 | - | linker |
| Gly 977 | - | linker |
| Ser 978 | - | linker |
| Gln 1144 | Glu 1144 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 103 | - | expression tag |
| Ser 104 | - | expression tag |
| Leu 105 | - | expression tag |
| Glu 106 | - | expression tag |
| Val 107 | - | expression tag |
| Leu 108 | - | expression tag |
| Phe 109 | - | expression tag |
| Gln 110 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65009.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 547.6 | |
| All* | Total formula weight | 65556.9 |
