8RO2

Integrative Structure of the human intron lariat Spliceosome (ILS'')

This is a non-PDB format compatible entry.

Summary for 8RO2

• Entry DOI: 10.2210/pdb8ro2/pdb
• Related: 8RO0 8RO1
• EMDB information: 19399
• Descriptor: U2 snRNA, Protein BUD31 homolog, Pre-mRNA-splicing factor RBM22, ... (40 entities in total)
• Functional Keywords: mrna, splicing, intron lariat spliceosome, pre-mrna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 40
• Total formula weight: 2326674.78

Authors

Rothe, P.,Vorlaender, M.K.,Plaschka, C. (deposition date: 2024-01-11, release date: 2024-09-18)

• Primary citation: Vorlander, M.K.,Rothe, P.,Kleifeld, J.,Cormack, E.D.,Veleti, L.,Riabov-Bassat, D.,Fin, L.,Phillips, A.W.,Cochella, L.,Plaschka, C.; Mechanism for the initiation of spliceosome disassembly.; Nature, 632:443-450, 2024; PubMed: 38925148; DOI: 10.1038/s41586-024-07741-1

Experimental method

ELECTRON MICROSCOPY (3.5 Å)