8RO0

Structure of the C. elegans Intron Lariat Spliceosome primed for disassembly (ILS')

This is a non-PDB format compatible entry.

Summary for 8RO0

• Entry DOI: 10.2210/pdb8ro0/pdb
• Related: 8RO1 8RO2 9FMD
• EMDB information: 19397
• Descriptor: U2 snRNA, TPR_REGION domain-containing protein, Pre-mRNA-splicing factor SPF27, ... (40 entities in total)
• Functional Keywords: mrna, splicing, intorn lariat spliceosome, ils, pre-mrna
• Biological source: Caenorhabditis elegans; More
• Total number of polymer chains: 46
• Total formula weight: 2302471.70

Authors

Vorlaender, M.K.,Rothe, P.,Plaschka, C. (deposition date: 2024-01-11, release date: 2024-08-07)

• Primary citation: Vorlander, M.K.,Rothe, P.,Kleifeld, J.,Cormack, E.,Veleti, L.,Riabov-Bassat, D.,Fin, L.,Phillips, A.W.,Cochella, L.,Plaschka, C.; Mechanism for the initiation of spliceosome disassembly.; Nature, 2024; PubMed: 38925148; DOI: 10.1038/s41586-024-07741-1

Experimental method

ELECTRON MICROSCOPY (2.9 Å)