8RMM

Structure of heteromeric CALHM2/4 channel in complex with synthetic nanobodies SbC2 and SbC4

Summary for 8RMM

• Entry DOI: 10.2210/pdb8rmm/pdb
• EMDB information: 19364
• Descriptor: Calcium homeostasis modulator protein 4, Synthetic nanobody SbC4, Calcium homeostasis modulator protein 2, ... (5 entities in total)
• Functional Keywords: ion channel, large pore channels, sybody, calhm, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 21
• Total formula weight: 545582.55

Authors

Drozdzyk, K.,Dutzler, R. (deposition date: 2024-01-08, release date: 2024-06-19, Last modification date: 2024-07-03)

• Primary citation: Drozdzyk, K.,Peter, M.,Dutzler, R.; Structural features of heteromeric channels composed of CALHM2 and CALHM4 paralogs.; Elife, 13:-, 2024; PubMed: 38896440; DOI: 10.7554/eLife.96138

Experimental method