8RML
Structure of heteromeric CALHM2/4 channel in complex with synthetic nanobody SbC4
Summary for 8RML
| Entry DOI | 10.2210/pdb8rml/pdb |
| EMDB information | 19363 |
| Descriptor | Calcium homeostasis modulator protein 4, Synthetic nanobody SbC4, Calcium homeostasis modulator protein 2 (3 entities in total) |
| Functional Keywords | ion channel, large pore channels, sybody, calhm, membrane protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 13 |
| Total formula weight | 430496.01 |
| Authors | Drozdzyk, K.,Dutzler, R. (deposition date: 2024-01-08, release date: 2024-06-19, Last modification date: 2024-07-03) |
| Primary citation | Drozdzyk, K.,Peter, M.,Dutzler, R. Structural features of heteromeric channels composed of CALHM2 and CALHM4 paralogs. Elife, 13:-, 2024 Cited by PubMed: 38896440DOI: 10.7554/eLife.96138 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.84 Å) |
Structure validation
Download full validation report
