8RMK

Cryo-EM structure of human CALHM2 in complex with synthetic nanobody SbC2

Summary for 8RMK

• Entry DOI: 10.2210/pdb8rmk/pdb
• EMDB information: 19362
• Descriptor: Calcium homeostasis modulator protein 2, Synthetic nanobody SbC2, DIUNDECYL PHOSPHATIDYL CHOLINE (3 entities in total)
• Functional Keywords: ion channel, large pore channels, sybody, calhm, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 22
• Total formula weight: 599782.80

Authors

Drozdzyk, K.,Dutzler, R. (deposition date: 2024-01-08, release date: 2024-06-19, Last modification date: 2024-07-03)

• Primary citation: Drozdzyk, K.,Peter, M.,Dutzler, R.; Structural features of heteromeric channels composed of CALHM2 and CALHM4 paralogs.; Elife, 13:-, 2024; PubMed: 38896440; DOI: 10.7554/eLife.96138

Experimental method

ELECTRON MICROSCOPY (3.07 Å)