8RM5
Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex
This is a non-PDB format compatible entry.
Summary for 8RM5
Entry DOI | 10.2210/pdb8rm5/pdb |
EMDB information | 19349 |
Descriptor | U6 snRNA-associated Sm-like protein LSm6, pre-mRNA, Splicing factor 3A subunit 2, ... (46 entities in total) |
Functional Keywords | spliceosome, splicing |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 60 |
Total formula weight | 2640919.22 |
Authors | Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.,Urlaub, H.,Kastner, B.,Stark, H.,Luehrmann, R. (deposition date: 2024-01-05, release date: 2024-05-22, Last modification date: 2024-07-10) |
Primary citation | Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.E.J.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R. Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630:1012-1019, 2024 Cited by PubMed: 38778104DOI: 10.1038/s41586-024-07458-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (6.9 Å) |
Structure validation
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