8RM5

Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
21	0000243	cellular_component	commitment complex
21	0000244	biological_process	spliceosomal tri-snRNP complex assembly
21	0000245	biological_process	spliceosomal complex assembly
21	0000387	biological_process	spliceosomal snRNP assembly
21	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
21	0000398	biological_process	mRNA splicing, via spliceosome
21	0003723	molecular_function	RNA binding
21	0005515	molecular_function	protein binding
21	0005634	cellular_component	nucleus
21	0005654	cellular_component	nucleoplasm
21	0005681	cellular_component	spliceosomal complex
21	0005682	cellular_component	U5 snRNP
21	0005684	cellular_component	U2-type spliceosomal complex
21	0005685	cellular_component	U1 snRNP
21	0005686	cellular_component	U2 snRNP
21	0005687	cellular_component	U4 snRNP
21	0005689	cellular_component	U12-type spliceosomal complex
21	0005737	cellular_component	cytoplasm
21	0005829	cellular_component	cytosol
21	0006396	biological_process	RNA processing
21	0006397	biological_process	mRNA processing
21	0008380	biological_process	RNA splicing
21	0030532	cellular_component	small nuclear ribonucleoprotein complex
21	0034709	cellular_component	methylosome
21	0034715	cellular_component	pICln-Sm protein complex
21	0034719	cellular_component	SMN-Sm protein complex
21	0036261	biological_process	7-methylguanosine cap hypermethylation
21	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
21	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
21	0071005	cellular_component	U2-type precatalytic spliceosome
21	0071007	cellular_component	U2-type catalytic step 2 spliceosome
21	0071011	cellular_component	precatalytic spliceosome
21	0071013	cellular_component	catalytic step 2 spliceosome
21	0097526	cellular_component	spliceosomal tri-snRNP complex
21	1903241	biological_process	U2-type prespliceosome assembly
21	1990446	molecular_function	U1 snRNP binding
21	1990904	cellular_component	ribonucleoprotein complex
22	0000244	biological_process	spliceosomal tri-snRNP complex assembly
22	0000245	biological_process	spliceosomal complex assembly
22	0000387	biological_process	spliceosomal snRNP assembly
22	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
22	0000398	biological_process	mRNA splicing, via spliceosome
22	0003723	molecular_function	RNA binding
22	0005515	molecular_function	protein binding
22	0005634	cellular_component	nucleus
22	0005654	cellular_component	nucleoplasm
22	0005681	cellular_component	spliceosomal complex
22	0005682	cellular_component	U5 snRNP
22	0005684	cellular_component	U2-type spliceosomal complex
22	0005685	cellular_component	U1 snRNP
22	0005686	cellular_component	U2 snRNP
22	0005687	cellular_component	U4 snRNP
22	0005689	cellular_component	U12-type spliceosomal complex
22	0005829	cellular_component	cytosol
22	0006397	biological_process	mRNA processing
22	0008380	biological_process	RNA splicing
22	0030532	cellular_component	small nuclear ribonucleoprotein complex
22	0034709	cellular_component	methylosome
22	0034715	cellular_component	pICln-Sm protein complex
22	0034719	cellular_component	SMN-Sm protein complex
22	0036261	biological_process	7-methylguanosine cap hypermethylation
22	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
22	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
22	0070062	cellular_component	extracellular exosome
22	0071005	cellular_component	U2-type precatalytic spliceosome
22	0071007	cellular_component	U2-type catalytic step 2 spliceosome
22	0071011	cellular_component	precatalytic spliceosome
22	0071013	cellular_component	catalytic step 2 spliceosome
22	0097525	cellular_component	spliceosomal snRNP complex
22	1903241	biological_process	U2-type prespliceosome assembly
22	1990904	cellular_component	ribonucleoprotein complex
23	0000243	cellular_component	commitment complex
23	0000244	biological_process	spliceosomal tri-snRNP complex assembly
23	0000245	biological_process	spliceosomal complex assembly
23	0000387	biological_process	spliceosomal snRNP assembly
23	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
23	0000398	biological_process	mRNA splicing, via spliceosome
23	0003723	molecular_function	RNA binding
23	0005515	molecular_function	protein binding
23	0005634	cellular_component	nucleus
23	0005654	cellular_component	nucleoplasm
23	0005681	cellular_component	spliceosomal complex
23	0005682	cellular_component	U5 snRNP
23	0005683	cellular_component	U7 snRNP
23	0005684	cellular_component	U2-type spliceosomal complex
23	0005685	cellular_component	U1 snRNP
23	0005686	cellular_component	U2 snRNP
23	0005687	cellular_component	U4 snRNP
23	0005689	cellular_component	U12-type spliceosomal complex
23	0005697	cellular_component	telomerase holoenzyme complex
23	0005737	cellular_component	cytoplasm
23	0005829	cellular_component	cytosol
23	0006396	biological_process	RNA processing
23	0006397	biological_process	mRNA processing
23	0006479	biological_process	protein methylation
23	0008380	biological_process	RNA splicing
23	0016604	cellular_component	nuclear body
23	0019899	molecular_function	enzyme binding
23	0030532	cellular_component	small nuclear ribonucleoprotein complex
23	0034709	cellular_component	methylosome
23	0034715	cellular_component	pICln-Sm protein complex
23	0034719	cellular_component	SMN-Sm protein complex
23	0036261	biological_process	7-methylguanosine cap hypermethylation
23	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
23	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
23	0070034	molecular_function	telomerase RNA binding
23	0071005	cellular_component	U2-type precatalytic spliceosome
23	0071007	cellular_component	U2-type catalytic step 2 spliceosome
23	0071011	cellular_component	precatalytic spliceosome
23	0071013	cellular_component	catalytic step 2 spliceosome
23	0071045	biological_process	nuclear histone mRNA catabolic process
23	0071208	molecular_function	histone pre-mRNA DCP binding
23	0071209	molecular_function	U7 snRNA binding
23	0097526	cellular_component	spliceosomal tri-snRNP complex
23	1903241	biological_process	U2-type prespliceosome assembly
23	1990904	cellular_component	ribonucleoprotein complex
2A	0000387	biological_process	spliceosomal snRNP assembly
2A	0000398	biological_process	mRNA splicing, via spliceosome
2A	0003723	molecular_function	RNA binding
2A	0005515	molecular_function	protein binding
2A	0005634	cellular_component	nucleus
2A	0005654	cellular_component	nucleoplasm
2A	0005681	cellular_component	spliceosomal complex
2A	0005684	cellular_component	U2-type spliceosomal complex
2A	0005686	cellular_component	U2 snRNP
2A	0006397	biological_process	mRNA processing
2A	0007283	biological_process	spermatogenesis
2A	0008380	biological_process	RNA splicing
2A	0016604	cellular_component	nuclear body
2A	0016607	cellular_component	nuclear speck
2A	0030532	cellular_component	small nuclear ribonucleoprotein complex
2A	0030620	molecular_function	U2 snRNA binding
2A	0071005	cellular_component	U2-type precatalytic spliceosome
2A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2A	0071013	cellular_component	catalytic step 2 spliceosome
2A	1903241	biological_process	U2-type prespliceosome assembly
2A	1990904	cellular_component	ribonucleoprotein complex
2B	0000387	biological_process	spliceosomal snRNP assembly
2B	0000398	biological_process	mRNA splicing, via spliceosome
2B	0003676	molecular_function	nucleic acid binding
2B	0003723	molecular_function	RNA binding
2B	0005515	molecular_function	protein binding
2B	0005634	cellular_component	nucleus
2B	0005654	cellular_component	nucleoplasm
2B	0005681	cellular_component	spliceosomal complex
2B	0005684	cellular_component	U2-type spliceosomal complex
2B	0005685	cellular_component	U1 snRNP
2B	0005686	cellular_component	U2 snRNP
2B	0006397	biological_process	mRNA processing
2B	0008380	biological_process	RNA splicing
2B	0016607	cellular_component	nuclear speck
2B	0030619	molecular_function	U1 snRNA binding
2B	0071005	cellular_component	U2-type precatalytic spliceosome
2B	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2B	0071013	cellular_component	catalytic step 2 spliceosome
2B	0097525	cellular_component	spliceosomal snRNP complex
2B	1903241	biological_process	U2-type prespliceosome assembly
2B	1990904	cellular_component	ribonucleoprotein complex
2b	0000244	biological_process	spliceosomal tri-snRNP complex assembly
2b	0000245	biological_process	spliceosomal complex assembly
2b	0000387	biological_process	spliceosomal snRNP assembly
2b	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
2b	0000398	biological_process	mRNA splicing, via spliceosome
2b	0003723	molecular_function	RNA binding
2b	0005515	molecular_function	protein binding
2b	0005634	cellular_component	nucleus
2b	0005654	cellular_component	nucleoplasm
2b	0005681	cellular_component	spliceosomal complex
2b	0005682	cellular_component	U5 snRNP
2b	0005683	cellular_component	U7 snRNP
2b	0005684	cellular_component	U2-type spliceosomal complex
2b	0005685	cellular_component	U1 snRNP
2b	0005686	cellular_component	U2 snRNP
2b	0005687	cellular_component	U4 snRNP
2b	0005689	cellular_component	U12-type spliceosomal complex
2b	0005697	cellular_component	telomerase holoenzyme complex
2b	0005737	cellular_component	cytoplasm
2b	0005829	cellular_component	cytosol
2b	0006397	biological_process	mRNA processing
2b	0006479	biological_process	protein methylation
2b	0008380	biological_process	RNA splicing
2b	0030532	cellular_component	small nuclear ribonucleoprotein complex
2b	0034709	cellular_component	methylosome
2b	0034719	cellular_component	SMN-Sm protein complex
2b	0036261	biological_process	7-methylguanosine cap hypermethylation
2b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2b	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
2b	0070034	molecular_function	telomerase RNA binding
2b	0070990	molecular_function	snRNP binding
2b	0071004	cellular_component	U2-type prespliceosome
2b	0071005	cellular_component	U2-type precatalytic spliceosome
2b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2b	0071013	cellular_component	catalytic step 2 spliceosome
2b	0071045	biological_process	nuclear histone mRNA catabolic process
2b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
2b	0071208	molecular_function	histone pre-mRNA DCP binding
2b	1903241	biological_process	U2-type prespliceosome assembly
2b	1990446	molecular_function	U1 snRNP binding
2b	1990447	molecular_function	U2 snRNP binding
2b	1990904	cellular_component	ribonucleoprotein complex
2e	0000244	biological_process	spliceosomal tri-snRNP complex assembly
2e	0000245	biological_process	spliceosomal complex assembly
2e	0000387	biological_process	spliceosomal snRNP assembly
2e	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
2e	0000398	biological_process	mRNA splicing, via spliceosome
2e	0003723	molecular_function	RNA binding
2e	0005515	molecular_function	protein binding
2e	0005634	cellular_component	nucleus
2e	0005654	cellular_component	nucleoplasm
2e	0005681	cellular_component	spliceosomal complex
2e	0005682	cellular_component	U5 snRNP
2e	0005683	cellular_component	U7 snRNP
2e	0005684	cellular_component	U2-type spliceosomal complex
2e	0005685	cellular_component	U1 snRNP
2e	0005686	cellular_component	U2 snRNP
2e	0005687	cellular_component	U4 snRNP
2e	0005689	cellular_component	U12-type spliceosomal complex
2e	0005697	cellular_component	telomerase holoenzyme complex
2e	0005829	cellular_component	cytosol
2e	0006397	biological_process	mRNA processing
2e	0008380	biological_process	RNA splicing
2e	0030532	cellular_component	small nuclear ribonucleoprotein complex
2e	0034709	cellular_component	methylosome
2e	0034715	cellular_component	pICln-Sm protein complex
2e	0034719	cellular_component	SMN-Sm protein complex
2e	0036261	biological_process	7-methylguanosine cap hypermethylation
2e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2e	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
2e	0071005	cellular_component	U2-type precatalytic spliceosome
2e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2e	0071011	cellular_component	precatalytic spliceosome
2e	0071013	cellular_component	catalytic step 2 spliceosome
2e	0071045	biological_process	nuclear histone mRNA catabolic process
2e	1903241	biological_process	U2-type prespliceosome assembly
2e	1990904	cellular_component	ribonucleoprotein complex
2f	0000244	biological_process	spliceosomal tri-snRNP complex assembly
2f	0000245	biological_process	spliceosomal complex assembly
2f	0000387	biological_process	spliceosomal snRNP assembly
2f	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
2f	0000398	biological_process	mRNA splicing, via spliceosome
2f	0003723	molecular_function	RNA binding
2f	0005515	molecular_function	protein binding
2f	0005634	cellular_component	nucleus
2f	0005654	cellular_component	nucleoplasm
2f	0005681	cellular_component	spliceosomal complex
2f	0005683	cellular_component	U7 snRNP
2f	0005684	cellular_component	U2-type spliceosomal complex
2f	0005685	cellular_component	U1 snRNP
2f	0005687	cellular_component	U4 snRNP
2f	0005689	cellular_component	U12-type spliceosomal complex
2f	0005829	cellular_component	cytosol
2f	0006397	biological_process	mRNA processing
2f	0008380	biological_process	RNA splicing
2f	0022618	biological_process	protein-RNA complex assembly
2f	0030532	cellular_component	small nuclear ribonucleoprotein complex
2f	0034709	cellular_component	methylosome
2f	0034715	cellular_component	pICln-Sm protein complex
2f	0034719	cellular_component	SMN-Sm protein complex
2f	0036261	biological_process	7-methylguanosine cap hypermethylation
2f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2f	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
2f	0071005	cellular_component	U2-type precatalytic spliceosome
2f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2f	0071013	cellular_component	catalytic step 2 spliceosome
2f	0071045	biological_process	nuclear histone mRNA catabolic process
2f	1903241	biological_process	U2-type prespliceosome assembly
2f	1990904	cellular_component	ribonucleoprotein complex
2g	0000244	biological_process	spliceosomal tri-snRNP complex assembly
2g	0000245	biological_process	spliceosomal complex assembly
2g	0000387	biological_process	spliceosomal snRNP assembly
2g	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
2g	0000398	biological_process	mRNA splicing, via spliceosome
2g	0003723	molecular_function	RNA binding
2g	0005515	molecular_function	protein binding
2g	0005634	cellular_component	nucleus
2g	0005654	cellular_component	nucleoplasm
2g	0005681	cellular_component	spliceosomal complex
2g	0005682	cellular_component	U5 snRNP
2g	0005683	cellular_component	U7 snRNP
2g	0005684	cellular_component	U2-type spliceosomal complex
2g	0005685	cellular_component	U1 snRNP
2g	0005686	cellular_component	U2 snRNP
2g	0005687	cellular_component	U4 snRNP
2g	0005689	cellular_component	U12-type spliceosomal complex
2g	0005829	cellular_component	cytosol
2g	0006397	biological_process	mRNA processing
2g	0008380	biological_process	RNA splicing
2g	0030532	cellular_component	small nuclear ribonucleoprotein complex
2g	0034709	cellular_component	methylosome
2g	0034719	cellular_component	SMN-Sm protein complex
2g	0036261	biological_process	7-methylguanosine cap hypermethylation
2g	0043186	cellular_component	P granule
2g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2g	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
2g	0071004	cellular_component	U2-type prespliceosome
2g	0071005	cellular_component	U2-type precatalytic spliceosome
2g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2g	0071011	cellular_component	precatalytic spliceosome
2g	0071013	cellular_component	catalytic step 2 spliceosome
2g	0071045	biological_process	nuclear histone mRNA catabolic process
2g	0097526	cellular_component	spliceosomal tri-snRNP complex
2g	1903241	biological_process	U2-type prespliceosome assembly
2g	1990904	cellular_component	ribonucleoprotein complex
41	0000243	cellular_component	commitment complex
41	0000244	biological_process	spliceosomal tri-snRNP complex assembly
41	0000245	biological_process	spliceosomal complex assembly
41	0000387	biological_process	spliceosomal snRNP assembly
41	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
41	0000398	biological_process	mRNA splicing, via spliceosome
41	0003723	molecular_function	RNA binding
41	0005515	molecular_function	protein binding
41	0005634	cellular_component	nucleus
41	0005654	cellular_component	nucleoplasm
41	0005681	cellular_component	spliceosomal complex
41	0005682	cellular_component	U5 snRNP
41	0005684	cellular_component	U2-type spliceosomal complex
41	0005685	cellular_component	U1 snRNP
41	0005686	cellular_component	U2 snRNP
41	0005687	cellular_component	U4 snRNP
41	0005689	cellular_component	U12-type spliceosomal complex
41	0005737	cellular_component	cytoplasm
41	0005829	cellular_component	cytosol
41	0006396	biological_process	RNA processing
41	0006397	biological_process	mRNA processing
41	0008380	biological_process	RNA splicing
41	0030532	cellular_component	small nuclear ribonucleoprotein complex
41	0034709	cellular_component	methylosome
41	0034715	cellular_component	pICln-Sm protein complex
41	0034719	cellular_component	SMN-Sm protein complex
41	0036261	biological_process	7-methylguanosine cap hypermethylation
41	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
41	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
41	0071005	cellular_component	U2-type precatalytic spliceosome
41	0071007	cellular_component	U2-type catalytic step 2 spliceosome
41	0071011	cellular_component	precatalytic spliceosome
41	0071013	cellular_component	catalytic step 2 spliceosome
41	0097526	cellular_component	spliceosomal tri-snRNP complex
41	1903241	biological_process	U2-type prespliceosome assembly
41	1990446	molecular_function	U1 snRNP binding
41	1990904	cellular_component	ribonucleoprotein complex
42	0000244	biological_process	spliceosomal tri-snRNP complex assembly
42	0000245	biological_process	spliceosomal complex assembly
42	0000387	biological_process	spliceosomal snRNP assembly
42	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
42	0000398	biological_process	mRNA splicing, via spliceosome
42	0003723	molecular_function	RNA binding
42	0005515	molecular_function	protein binding
42	0005634	cellular_component	nucleus
42	0005654	cellular_component	nucleoplasm
42	0005681	cellular_component	spliceosomal complex
42	0005682	cellular_component	U5 snRNP
42	0005684	cellular_component	U2-type spliceosomal complex
42	0005685	cellular_component	U1 snRNP
42	0005686	cellular_component	U2 snRNP
42	0005687	cellular_component	U4 snRNP
42	0005689	cellular_component	U12-type spliceosomal complex
42	0005829	cellular_component	cytosol
42	0006397	biological_process	mRNA processing
42	0008380	biological_process	RNA splicing
42	0030532	cellular_component	small nuclear ribonucleoprotein complex
42	0034709	cellular_component	methylosome
42	0034715	cellular_component	pICln-Sm protein complex
42	0034719	cellular_component	SMN-Sm protein complex
42	0036261	biological_process	7-methylguanosine cap hypermethylation
42	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
42	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
42	0070062	cellular_component	extracellular exosome
42	0071005	cellular_component	U2-type precatalytic spliceosome
42	0071007	cellular_component	U2-type catalytic step 2 spliceosome
42	0071011	cellular_component	precatalytic spliceosome
42	0071013	cellular_component	catalytic step 2 spliceosome
42	0097525	cellular_component	spliceosomal snRNP complex
42	1903241	biological_process	U2-type prespliceosome assembly
42	1990904	cellular_component	ribonucleoprotein complex
43	0000243	cellular_component	commitment complex
43	0000244	biological_process	spliceosomal tri-snRNP complex assembly
43	0000245	biological_process	spliceosomal complex assembly
43	0000387	biological_process	spliceosomal snRNP assembly
43	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
43	0000398	biological_process	mRNA splicing, via spliceosome
43	0003723	molecular_function	RNA binding
43	0005515	molecular_function	protein binding
43	0005634	cellular_component	nucleus
43	0005654	cellular_component	nucleoplasm
43	0005681	cellular_component	spliceosomal complex
43	0005682	cellular_component	U5 snRNP
43	0005683	cellular_component	U7 snRNP
43	0005684	cellular_component	U2-type spliceosomal complex
43	0005685	cellular_component	U1 snRNP
43	0005686	cellular_component	U2 snRNP
43	0005687	cellular_component	U4 snRNP
43	0005689	cellular_component	U12-type spliceosomal complex
43	0005697	cellular_component	telomerase holoenzyme complex
43	0005737	cellular_component	cytoplasm
43	0005829	cellular_component	cytosol
43	0006396	biological_process	RNA processing
43	0006397	biological_process	mRNA processing
43	0006479	biological_process	protein methylation
43	0008380	biological_process	RNA splicing
43	0016604	cellular_component	nuclear body
43	0019899	molecular_function	enzyme binding
43	0030532	cellular_component	small nuclear ribonucleoprotein complex
43	0034709	cellular_component	methylosome
43	0034715	cellular_component	pICln-Sm protein complex
43	0034719	cellular_component	SMN-Sm protein complex
43	0036261	biological_process	7-methylguanosine cap hypermethylation
43	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
43	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
43	0070034	molecular_function	telomerase RNA binding
43	0071005	cellular_component	U2-type precatalytic spliceosome
43	0071007	cellular_component	U2-type catalytic step 2 spliceosome
43	0071011	cellular_component	precatalytic spliceosome
43	0071013	cellular_component	catalytic step 2 spliceosome
43	0071045	biological_process	nuclear histone mRNA catabolic process
43	0071208	molecular_function	histone pre-mRNA DCP binding
43	0071209	molecular_function	U7 snRNA binding
43	0097526	cellular_component	spliceosomal tri-snRNP complex
43	1903241	biological_process	U2-type prespliceosome assembly
43	1990904	cellular_component	ribonucleoprotein complex
4b	0000244	biological_process	spliceosomal tri-snRNP complex assembly
4b	0000245	biological_process	spliceosomal complex assembly
4b	0000387	biological_process	spliceosomal snRNP assembly
4b	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
4b	0000398	biological_process	mRNA splicing, via spliceosome
4b	0003723	molecular_function	RNA binding
4b	0005515	molecular_function	protein binding
4b	0005634	cellular_component	nucleus
4b	0005654	cellular_component	nucleoplasm
4b	0005681	cellular_component	spliceosomal complex
4b	0005682	cellular_component	U5 snRNP
4b	0005683	cellular_component	U7 snRNP
4b	0005684	cellular_component	U2-type spliceosomal complex
4b	0005685	cellular_component	U1 snRNP
4b	0005686	cellular_component	U2 snRNP
4b	0005687	cellular_component	U4 snRNP
4b	0005689	cellular_component	U12-type spliceosomal complex
4b	0005697	cellular_component	telomerase holoenzyme complex
4b	0005737	cellular_component	cytoplasm
4b	0005829	cellular_component	cytosol
4b	0006397	biological_process	mRNA processing
4b	0006479	biological_process	protein methylation
4b	0008380	biological_process	RNA splicing
4b	0030532	cellular_component	small nuclear ribonucleoprotein complex
4b	0034709	cellular_component	methylosome
4b	0034719	cellular_component	SMN-Sm protein complex
4b	0036261	biological_process	7-methylguanosine cap hypermethylation
4b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
4b	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
4b	0070034	molecular_function	telomerase RNA binding
4b	0070990	molecular_function	snRNP binding
4b	0071004	cellular_component	U2-type prespliceosome
4b	0071005	cellular_component	U2-type precatalytic spliceosome
4b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
4b	0071013	cellular_component	catalytic step 2 spliceosome
4b	0071045	biological_process	nuclear histone mRNA catabolic process
4b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
4b	0071208	molecular_function	histone pre-mRNA DCP binding
4b	1903241	biological_process	U2-type prespliceosome assembly
4b	1990446	molecular_function	U1 snRNP binding
4b	1990447	molecular_function	U2 snRNP binding
4b	1990904	cellular_component	ribonucleoprotein complex
4e	0000244	biological_process	spliceosomal tri-snRNP complex assembly
4e	0000245	biological_process	spliceosomal complex assembly
4e	0000387	biological_process	spliceosomal snRNP assembly
4e	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
4e	0000398	biological_process	mRNA splicing, via spliceosome
4e	0003723	molecular_function	RNA binding
4e	0005515	molecular_function	protein binding
4e	0005634	cellular_component	nucleus
4e	0005654	cellular_component	nucleoplasm
4e	0005681	cellular_component	spliceosomal complex
4e	0005682	cellular_component	U5 snRNP
4e	0005683	cellular_component	U7 snRNP
4e	0005684	cellular_component	U2-type spliceosomal complex
4e	0005685	cellular_component	U1 snRNP
4e	0005686	cellular_component	U2 snRNP
4e	0005687	cellular_component	U4 snRNP
4e	0005689	cellular_component	U12-type spliceosomal complex
4e	0005697	cellular_component	telomerase holoenzyme complex
4e	0005829	cellular_component	cytosol
4e	0006397	biological_process	mRNA processing
4e	0008380	biological_process	RNA splicing
4e	0030532	cellular_component	small nuclear ribonucleoprotein complex
4e	0034709	cellular_component	methylosome
4e	0034715	cellular_component	pICln-Sm protein complex
4e	0034719	cellular_component	SMN-Sm protein complex
4e	0036261	biological_process	7-methylguanosine cap hypermethylation
4e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
4e	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
4e	0071005	cellular_component	U2-type precatalytic spliceosome
4e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
4e	0071011	cellular_component	precatalytic spliceosome
4e	0071013	cellular_component	catalytic step 2 spliceosome
4e	0071045	biological_process	nuclear histone mRNA catabolic process
4e	1903241	biological_process	U2-type prespliceosome assembly
4e	1990904	cellular_component	ribonucleoprotein complex
4f	0000244	biological_process	spliceosomal tri-snRNP complex assembly
4f	0000245	biological_process	spliceosomal complex assembly
4f	0000387	biological_process	spliceosomal snRNP assembly
4f	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
4f	0000398	biological_process	mRNA splicing, via spliceosome
4f	0003723	molecular_function	RNA binding
4f	0005515	molecular_function	protein binding
4f	0005634	cellular_component	nucleus
4f	0005654	cellular_component	nucleoplasm
4f	0005681	cellular_component	spliceosomal complex
4f	0005683	cellular_component	U7 snRNP
4f	0005684	cellular_component	U2-type spliceosomal complex
4f	0005685	cellular_component	U1 snRNP
4f	0005687	cellular_component	U4 snRNP
4f	0005689	cellular_component	U12-type spliceosomal complex
4f	0005829	cellular_component	cytosol
4f	0006397	biological_process	mRNA processing
4f	0008380	biological_process	RNA splicing
4f	0022618	biological_process	protein-RNA complex assembly
4f	0030532	cellular_component	small nuclear ribonucleoprotein complex
4f	0034709	cellular_component	methylosome
4f	0034715	cellular_component	pICln-Sm protein complex
4f	0034719	cellular_component	SMN-Sm protein complex
4f	0036261	biological_process	7-methylguanosine cap hypermethylation
4f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
4f	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
4f	0071005	cellular_component	U2-type precatalytic spliceosome
4f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
4f	0071013	cellular_component	catalytic step 2 spliceosome
4f	0071045	biological_process	nuclear histone mRNA catabolic process
4f	1903241	biological_process	U2-type prespliceosome assembly
4f	1990904	cellular_component	ribonucleoprotein complex
4g	0000244	biological_process	spliceosomal tri-snRNP complex assembly
4g	0000245	biological_process	spliceosomal complex assembly
4g	0000387	biological_process	spliceosomal snRNP assembly
4g	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
4g	0000398	biological_process	mRNA splicing, via spliceosome
4g	0003723	molecular_function	RNA binding
4g	0005515	molecular_function	protein binding
4g	0005634	cellular_component	nucleus
4g	0005654	cellular_component	nucleoplasm
4g	0005681	cellular_component	spliceosomal complex
4g	0005682	cellular_component	U5 snRNP
4g	0005683	cellular_component	U7 snRNP
4g	0005684	cellular_component	U2-type spliceosomal complex
4g	0005685	cellular_component	U1 snRNP
4g	0005686	cellular_component	U2 snRNP
4g	0005687	cellular_component	U4 snRNP
4g	0005689	cellular_component	U12-type spliceosomal complex
4g	0005829	cellular_component	cytosol
4g	0006397	biological_process	mRNA processing
4g	0008380	biological_process	RNA splicing
4g	0030532	cellular_component	small nuclear ribonucleoprotein complex
4g	0034709	cellular_component	methylosome
4g	0034719	cellular_component	SMN-Sm protein complex
4g	0036261	biological_process	7-methylguanosine cap hypermethylation
4g	0043186	cellular_component	P granule
4g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
4g	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
4g	0071004	cellular_component	U2-type prespliceosome
4g	0071005	cellular_component	U2-type precatalytic spliceosome
4g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
4g	0071011	cellular_component	precatalytic spliceosome
4g	0071013	cellular_component	catalytic step 2 spliceosome
4g	0071045	biological_process	nuclear histone mRNA catabolic process
4g	0097526	cellular_component	spliceosomal tri-snRNP complex
4g	1903241	biological_process	U2-type prespliceosome assembly
4g	1990904	cellular_component	ribonucleoprotein complex
51	0000243	cellular_component	commitment complex
51	0000244	biological_process	spliceosomal tri-snRNP complex assembly
51	0000245	biological_process	spliceosomal complex assembly
51	0000387	biological_process	spliceosomal snRNP assembly
51	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
51	0000398	biological_process	mRNA splicing, via spliceosome
51	0003723	molecular_function	RNA binding
51	0005515	molecular_function	protein binding
51	0005634	cellular_component	nucleus
51	0005654	cellular_component	nucleoplasm
51	0005681	cellular_component	spliceosomal complex
51	0005682	cellular_component	U5 snRNP
51	0005684	cellular_component	U2-type spliceosomal complex
51	0005685	cellular_component	U1 snRNP
51	0005686	cellular_component	U2 snRNP
51	0005687	cellular_component	U4 snRNP
51	0005689	cellular_component	U12-type spliceosomal complex
51	0005737	cellular_component	cytoplasm
51	0005829	cellular_component	cytosol
51	0006396	biological_process	RNA processing
51	0006397	biological_process	mRNA processing
51	0008380	biological_process	RNA splicing
51	0030532	cellular_component	small nuclear ribonucleoprotein complex
51	0034709	cellular_component	methylosome
51	0034715	cellular_component	pICln-Sm protein complex
51	0034719	cellular_component	SMN-Sm protein complex
51	0036261	biological_process	7-methylguanosine cap hypermethylation
51	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
51	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
51	0071005	cellular_component	U2-type precatalytic spliceosome
51	0071007	cellular_component	U2-type catalytic step 2 spliceosome
51	0071011	cellular_component	precatalytic spliceosome
51	0071013	cellular_component	catalytic step 2 spliceosome
51	0097526	cellular_component	spliceosomal tri-snRNP complex
51	1903241	biological_process	U2-type prespliceosome assembly
51	1990446	molecular_function	U1 snRNP binding
51	1990904	cellular_component	ribonucleoprotein complex
52	0000244	biological_process	spliceosomal tri-snRNP complex assembly
52	0000245	biological_process	spliceosomal complex assembly
52	0000387	biological_process	spliceosomal snRNP assembly
52	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
52	0000398	biological_process	mRNA splicing, via spliceosome
52	0003723	molecular_function	RNA binding
52	0005515	molecular_function	protein binding
52	0005634	cellular_component	nucleus
52	0005654	cellular_component	nucleoplasm
52	0005681	cellular_component	spliceosomal complex
52	0005682	cellular_component	U5 snRNP
52	0005684	cellular_component	U2-type spliceosomal complex
52	0005685	cellular_component	U1 snRNP
52	0005686	cellular_component	U2 snRNP
52	0005687	cellular_component	U4 snRNP
52	0005689	cellular_component	U12-type spliceosomal complex
52	0005829	cellular_component	cytosol
52	0006397	biological_process	mRNA processing
52	0008380	biological_process	RNA splicing
52	0030532	cellular_component	small nuclear ribonucleoprotein complex
52	0034709	cellular_component	methylosome
52	0034715	cellular_component	pICln-Sm protein complex
52	0034719	cellular_component	SMN-Sm protein complex
52	0036261	biological_process	7-methylguanosine cap hypermethylation
52	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
52	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
52	0070062	cellular_component	extracellular exosome
52	0071005	cellular_component	U2-type precatalytic spliceosome
52	0071007	cellular_component	U2-type catalytic step 2 spliceosome
52	0071011	cellular_component	precatalytic spliceosome
52	0071013	cellular_component	catalytic step 2 spliceosome
52	0097525	cellular_component	spliceosomal snRNP complex
52	1903241	biological_process	U2-type prespliceosome assembly
52	1990904	cellular_component	ribonucleoprotein complex
53	0000243	cellular_component	commitment complex
53	0000244	biological_process	spliceosomal tri-snRNP complex assembly
53	0000245	biological_process	spliceosomal complex assembly
53	0000387	biological_process	spliceosomal snRNP assembly
53	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
53	0000398	biological_process	mRNA splicing, via spliceosome
53	0003723	molecular_function	RNA binding
53	0005515	molecular_function	protein binding
53	0005634	cellular_component	nucleus
53	0005654	cellular_component	nucleoplasm
53	0005681	cellular_component	spliceosomal complex
53	0005682	cellular_component	U5 snRNP
53	0005683	cellular_component	U7 snRNP
53	0005684	cellular_component	U2-type spliceosomal complex
53	0005685	cellular_component	U1 snRNP
53	0005686	cellular_component	U2 snRNP
53	0005687	cellular_component	U4 snRNP
53	0005689	cellular_component	U12-type spliceosomal complex
53	0005697	cellular_component	telomerase holoenzyme complex
53	0005737	cellular_component	cytoplasm
53	0005829	cellular_component	cytosol
53	0006396	biological_process	RNA processing
53	0006397	biological_process	mRNA processing
53	0006479	biological_process	protein methylation
53	0008380	biological_process	RNA splicing
53	0016604	cellular_component	nuclear body
53	0019899	molecular_function	enzyme binding
53	0030532	cellular_component	small nuclear ribonucleoprotein complex
53	0034709	cellular_component	methylosome
53	0034715	cellular_component	pICln-Sm protein complex
53	0034719	cellular_component	SMN-Sm protein complex
53	0036261	biological_process	7-methylguanosine cap hypermethylation
53	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
53	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
53	0070034	molecular_function	telomerase RNA binding
53	0071005	cellular_component	U2-type precatalytic spliceosome
53	0071007	cellular_component	U2-type catalytic step 2 spliceosome
53	0071011	cellular_component	precatalytic spliceosome
53	0071013	cellular_component	catalytic step 2 spliceosome
53	0071045	biological_process	nuclear histone mRNA catabolic process
53	0071208	molecular_function	histone pre-mRNA DCP binding
53	0071209	molecular_function	U7 snRNA binding
53	0097526	cellular_component	spliceosomal tri-snRNP complex
53	1903241	biological_process	U2-type prespliceosome assembly
53	1990904	cellular_component	ribonucleoprotein complex
5b	0000244	biological_process	spliceosomal tri-snRNP complex assembly
5b	0000245	biological_process	spliceosomal complex assembly
5b	0000387	biological_process	spliceosomal snRNP assembly
5b	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
5b	0000398	biological_process	mRNA splicing, via spliceosome
5b	0003723	molecular_function	RNA binding
5b	0005515	molecular_function	protein binding
5b	0005634	cellular_component	nucleus
5b	0005654	cellular_component	nucleoplasm
5b	0005681	cellular_component	spliceosomal complex
5b	0005682	cellular_component	U5 snRNP
5b	0005683	cellular_component	U7 snRNP
5b	0005684	cellular_component	U2-type spliceosomal complex
5b	0005685	cellular_component	U1 snRNP
5b	0005686	cellular_component	U2 snRNP
5b	0005687	cellular_component	U4 snRNP
5b	0005689	cellular_component	U12-type spliceosomal complex
5b	0005697	cellular_component	telomerase holoenzyme complex
5b	0005737	cellular_component	cytoplasm
5b	0005829	cellular_component	cytosol
5b	0006397	biological_process	mRNA processing
5b	0006479	biological_process	protein methylation
5b	0008380	biological_process	RNA splicing
5b	0030532	cellular_component	small nuclear ribonucleoprotein complex
5b	0034709	cellular_component	methylosome
5b	0034719	cellular_component	SMN-Sm protein complex
5b	0036261	biological_process	7-methylguanosine cap hypermethylation
5b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5b	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
5b	0070034	molecular_function	telomerase RNA binding
5b	0070990	molecular_function	snRNP binding
5b	0071004	cellular_component	U2-type prespliceosome
5b	0071005	cellular_component	U2-type precatalytic spliceosome
5b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5b	0071013	cellular_component	catalytic step 2 spliceosome
5b	0071045	biological_process	nuclear histone mRNA catabolic process
5b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
5b	0071208	molecular_function	histone pre-mRNA DCP binding
5b	1903241	biological_process	U2-type prespliceosome assembly
5b	1990446	molecular_function	U1 snRNP binding
5b	1990447	molecular_function	U2 snRNP binding
5b	1990904	cellular_component	ribonucleoprotein complex
5e	0000244	biological_process	spliceosomal tri-snRNP complex assembly
5e	0000245	biological_process	spliceosomal complex assembly
5e	0000387	biological_process	spliceosomal snRNP assembly
5e	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
5e	0000398	biological_process	mRNA splicing, via spliceosome
5e	0003723	molecular_function	RNA binding
5e	0005515	molecular_function	protein binding
5e	0005634	cellular_component	nucleus
5e	0005654	cellular_component	nucleoplasm
5e	0005681	cellular_component	spliceosomal complex
5e	0005682	cellular_component	U5 snRNP
5e	0005683	cellular_component	U7 snRNP
5e	0005684	cellular_component	U2-type spliceosomal complex
5e	0005685	cellular_component	U1 snRNP
5e	0005686	cellular_component	U2 snRNP
5e	0005687	cellular_component	U4 snRNP
5e	0005689	cellular_component	U12-type spliceosomal complex
5e	0005697	cellular_component	telomerase holoenzyme complex
5e	0005829	cellular_component	cytosol
5e	0006397	biological_process	mRNA processing
5e	0008380	biological_process	RNA splicing
5e	0030532	cellular_component	small nuclear ribonucleoprotein complex
5e	0034709	cellular_component	methylosome
5e	0034715	cellular_component	pICln-Sm protein complex
5e	0034719	cellular_component	SMN-Sm protein complex
5e	0036261	biological_process	7-methylguanosine cap hypermethylation
5e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5e	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
5e	0071005	cellular_component	U2-type precatalytic spliceosome
5e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5e	0071011	cellular_component	precatalytic spliceosome
5e	0071013	cellular_component	catalytic step 2 spliceosome
5e	0071045	biological_process	nuclear histone mRNA catabolic process
5e	1903241	biological_process	U2-type prespliceosome assembly
5e	1990904	cellular_component	ribonucleoprotein complex
5f	0000244	biological_process	spliceosomal tri-snRNP complex assembly
5f	0000245	biological_process	spliceosomal complex assembly
5f	0000387	biological_process	spliceosomal snRNP assembly
5f	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
5f	0000398	biological_process	mRNA splicing, via spliceosome
5f	0003723	molecular_function	RNA binding
5f	0005515	molecular_function	protein binding
5f	0005634	cellular_component	nucleus
5f	0005654	cellular_component	nucleoplasm
5f	0005681	cellular_component	spliceosomal complex
5f	0005683	cellular_component	U7 snRNP
5f	0005684	cellular_component	U2-type spliceosomal complex
5f	0005685	cellular_component	U1 snRNP
5f	0005687	cellular_component	U4 snRNP
5f	0005689	cellular_component	U12-type spliceosomal complex
5f	0005829	cellular_component	cytosol
5f	0006397	biological_process	mRNA processing
5f	0008380	biological_process	RNA splicing
5f	0022618	biological_process	protein-RNA complex assembly
5f	0030532	cellular_component	small nuclear ribonucleoprotein complex
5f	0034709	cellular_component	methylosome
5f	0034715	cellular_component	pICln-Sm protein complex
5f	0034719	cellular_component	SMN-Sm protein complex
5f	0036261	biological_process	7-methylguanosine cap hypermethylation
5f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5f	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
5f	0071005	cellular_component	U2-type precatalytic spliceosome
5f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5f	0071013	cellular_component	catalytic step 2 spliceosome
5f	0071045	biological_process	nuclear histone mRNA catabolic process
5f	1903241	biological_process	U2-type prespliceosome assembly
5f	1990904	cellular_component	ribonucleoprotein complex
5g	0000244	biological_process	spliceosomal tri-snRNP complex assembly
5g	0000245	biological_process	spliceosomal complex assembly
5g	0000387	biological_process	spliceosomal snRNP assembly
5g	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
5g	0000398	biological_process	mRNA splicing, via spliceosome
5g	0003723	molecular_function	RNA binding
5g	0005515	molecular_function	protein binding
5g	0005634	cellular_component	nucleus
5g	0005654	cellular_component	nucleoplasm
5g	0005681	cellular_component	spliceosomal complex
5g	0005682	cellular_component	U5 snRNP
5g	0005683	cellular_component	U7 snRNP
5g	0005684	cellular_component	U2-type spliceosomal complex
5g	0005685	cellular_component	U1 snRNP
5g	0005686	cellular_component	U2 snRNP
5g	0005687	cellular_component	U4 snRNP
5g	0005689	cellular_component	U12-type spliceosomal complex
5g	0005829	cellular_component	cytosol
5g	0006397	biological_process	mRNA processing
5g	0008380	biological_process	RNA splicing
5g	0030532	cellular_component	small nuclear ribonucleoprotein complex
5g	0034709	cellular_component	methylosome
5g	0034719	cellular_component	SMN-Sm protein complex
5g	0036261	biological_process	7-methylguanosine cap hypermethylation
5g	0043186	cellular_component	P granule
5g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5g	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
5g	0071004	cellular_component	U2-type prespliceosome
5g	0071005	cellular_component	U2-type precatalytic spliceosome
5g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5g	0071011	cellular_component	precatalytic spliceosome
5g	0071013	cellular_component	catalytic step 2 spliceosome
5g	0071045	biological_process	nuclear histone mRNA catabolic process
5g	0097526	cellular_component	spliceosomal tri-snRNP complex
5g	1903241	biological_process	U2-type prespliceosome assembly
5g	1990904	cellular_component	ribonucleoprotein complex
62	0000244	biological_process	spliceosomal tri-snRNP complex assembly
62	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
62	0000387	biological_process	spliceosomal snRNP assembly
62	0000398	biological_process	mRNA splicing, via spliceosome
62	0000932	cellular_component	P-body
62	0003723	molecular_function	RNA binding
62	0005634	cellular_component	nucleus
62	0005654	cellular_component	nucleoplasm
62	0005681	cellular_component	spliceosomal complex
62	0005688	cellular_component	U6 snRNP
62	0005737	cellular_component	cytoplasm
62	0005829	cellular_component	cytosol
62	0006397	biological_process	mRNA processing
62	0006402	biological_process	mRNA catabolic process
62	0008380	biological_process	RNA splicing
62	0017070	molecular_function	U6 snRNA binding
62	0031267	molecular_function	small GTPase binding
62	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
62	0071005	cellular_component	U2-type precatalytic spliceosome
62	0071011	cellular_component	precatalytic spliceosome
62	0071013	cellular_component	catalytic step 2 spliceosome
62	0120115	cellular_component	Lsm2-8 complex
62	1990726	cellular_component	Lsm1-7-Pat1 complex
62	1990904	cellular_component	ribonucleoprotein complex
63	0000244	biological_process	spliceosomal tri-snRNP complex assembly
63	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
63	0000387	biological_process	spliceosomal snRNP assembly
63	0000398	biological_process	mRNA splicing, via spliceosome
63	0000932	cellular_component	P-body
63	0003723	molecular_function	RNA binding
63	0005515	molecular_function	protein binding
63	0005634	cellular_component	nucleus
63	0005654	cellular_component	nucleoplasm
63	0005681	cellular_component	spliceosomal complex
63	0005688	cellular_component	U6 snRNP
63	0005737	cellular_component	cytoplasm
63	0005829	cellular_component	cytosol
63	0006397	biological_process	mRNA processing
63	0008380	biological_process	RNA splicing
63	0030629	molecular_function	U6 snRNA 3'-end binding
63	0033962	biological_process	P-body assembly
63	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
63	0071005	cellular_component	U2-type precatalytic spliceosome
63	0071011	cellular_component	precatalytic spliceosome
63	0071013	cellular_component	catalytic step 2 spliceosome
63	0120115	cellular_component	Lsm2-8 complex
63	1990726	cellular_component	Lsm1-7-Pat1 complex
63	1990904	cellular_component	ribonucleoprotein complex
64	0000244	biological_process	spliceosomal tri-snRNP complex assembly
64	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
64	0000387	biological_process	spliceosomal snRNP assembly
64	0000398	biological_process	mRNA splicing, via spliceosome
64	0000932	cellular_component	P-body
64	0000956	biological_process	nuclear-transcribed mRNA catabolic process
64	0003723	molecular_function	RNA binding
64	0005515	molecular_function	protein binding
64	0005634	cellular_component	nucleus
64	0005654	cellular_component	nucleoplasm
64	0005681	cellular_component	spliceosomal complex
64	0005688	cellular_component	U6 snRNP
64	0005737	cellular_component	cytoplasm
64	0005829	cellular_component	cytosol
64	0006396	biological_process	RNA processing
64	0006397	biological_process	mRNA processing
64	0008380	biological_process	RNA splicing
64	0016020	cellular_component	membrane
64	0017070	molecular_function	U6 snRNA binding
64	0032991	cellular_component	protein-containing complex
64	0033962	biological_process	P-body assembly
64	0042731	molecular_function	PH domain binding
64	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
64	0071005	cellular_component	U2-type precatalytic spliceosome
64	0097526	cellular_component	spliceosomal tri-snRNP complex
64	0120115	cellular_component	Lsm2-8 complex
64	1990904	cellular_component	ribonucleoprotein complex
65	0000244	biological_process	spliceosomal tri-snRNP complex assembly
65	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
65	0000387	biological_process	spliceosomal snRNP assembly
65	0000398	biological_process	mRNA splicing, via spliceosome
65	0003723	molecular_function	RNA binding
65	0005634	cellular_component	nucleus
65	0005654	cellular_component	nucleoplasm
65	0005681	cellular_component	spliceosomal complex
65	0005688	cellular_component	U6 snRNP
65	0005737	cellular_component	cytoplasm
65	0005829	cellular_component	cytosol
65	0006397	biological_process	mRNA processing
65	0006402	biological_process	mRNA catabolic process
65	0008380	biological_process	RNA splicing
65	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
65	0046982	molecular_function	protein heterodimerization activity
65	0071005	cellular_component	U2-type precatalytic spliceosome
65	0120115	cellular_component	Lsm2-8 complex
65	1990726	cellular_component	Lsm1-7-Pat1 complex
65	1990904	cellular_component	ribonucleoprotein complex
66	0000244	biological_process	spliceosomal tri-snRNP complex assembly
66	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
66	0000387	biological_process	spliceosomal snRNP assembly
66	0000398	biological_process	mRNA splicing, via spliceosome
66	0000932	cellular_component	P-body
66	0003723	molecular_function	RNA binding
66	0005515	molecular_function	protein binding
66	0005634	cellular_component	nucleus
66	0005654	cellular_component	nucleoplasm
66	0005681	cellular_component	spliceosomal complex
66	0005688	cellular_component	U6 snRNP
66	0005730	cellular_component	nucleolus
66	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
66	0005737	cellular_component	cytoplasm
66	0005829	cellular_component	cytosol
66	0006364	biological_process	rRNA processing
66	0006397	biological_process	mRNA processing
66	0006402	biological_process	mRNA catabolic process
66	0008033	biological_process	tRNA processing
66	0008380	biological_process	RNA splicing
66	0030490	biological_process	maturation of SSU-rRNA
66	0030532	cellular_component	small nuclear ribonucleoprotein complex
66	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
66	0046982	molecular_function	protein heterodimerization activity
66	0071005	cellular_component	U2-type precatalytic spliceosome
66	0120115	cellular_component	Lsm2-8 complex
66	1990904	cellular_component	ribonucleoprotein complex
67	0000244	biological_process	spliceosomal tri-snRNP complex assembly
67	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
67	0000387	biological_process	spliceosomal snRNP assembly
67	0000398	biological_process	mRNA splicing, via spliceosome
67	0000956	biological_process	nuclear-transcribed mRNA catabolic process
67	0003723	molecular_function	RNA binding
67	0005515	molecular_function	protein binding
67	0005634	cellular_component	nucleus
67	0005654	cellular_component	nucleoplasm
67	0005681	cellular_component	spliceosomal complex
67	0005688	cellular_component	U6 snRNP
67	0005689	cellular_component	U12-type spliceosomal complex
67	0005737	cellular_component	cytoplasm
67	0005829	cellular_component	cytosol
67	0006397	biological_process	mRNA processing
67	0008380	biological_process	RNA splicing
67	0017070	molecular_function	U6 snRNA binding
67	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
67	0071004	cellular_component	U2-type prespliceosome
67	0071005	cellular_component	U2-type precatalytic spliceosome
67	0071013	cellular_component	catalytic step 2 spliceosome
67	0097526	cellular_component	spliceosomal tri-snRNP complex
67	0120115	cellular_component	Lsm2-8 complex
67	1990726	cellular_component	Lsm1-7-Pat1 complex
67	1990904	cellular_component	ribonucleoprotein complex
68	0000244	biological_process	spliceosomal tri-snRNP complex assembly
68	0000387	biological_process	spliceosomal snRNP assembly
68	0000398	biological_process	mRNA splicing, via spliceosome
68	0003723	molecular_function	RNA binding
68	0003729	molecular_function	mRNA binding
68	0005515	molecular_function	protein binding
68	0005634	cellular_component	nucleus
68	0005654	cellular_component	nucleoplasm
68	0005681	cellular_component	spliceosomal complex
68	0005688	cellular_component	U6 snRNP
68	0006397	biological_process	mRNA processing
68	0008380	biological_process	RNA splicing
68	0017070	molecular_function	U6 snRNA binding
68	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
68	0071005	cellular_component	U2-type precatalytic spliceosome
68	0071011	cellular_component	precatalytic spliceosome
68	0120115	cellular_component	Lsm2-8 complex
68	1990904	cellular_component	ribonucleoprotein complex
7	0000387	biological_process	spliceosomal snRNP assembly
7	0000389	biological_process	mRNA 3'-splice site recognition
7	0000398	biological_process	mRNA splicing, via spliceosome
7	0003723	molecular_function	RNA binding
7	0005515	molecular_function	protein binding
7	0005634	cellular_component	nucleus
7	0005654	cellular_component	nucleoplasm
7	0005681	cellular_component	spliceosomal complex
7	0005684	cellular_component	U2-type spliceosomal complex
7	0005686	cellular_component	U2 snRNP
7	0006396	biological_process	RNA processing
7	0006397	biological_process	mRNA processing
7	0008380	biological_process	RNA splicing
7	0016607	cellular_component	nuclear speck
7	0045292	biological_process	mRNA cis splicing, via spliceosome
7	0071004	cellular_component	U2-type prespliceosome
7	0071005	cellular_component	U2-type precatalytic spliceosome
7	0071013	cellular_component	catalytic step 2 spliceosome
7	1903241	biological_process	U2-type prespliceosome assembly
8	0000245	biological_process	spliceosomal complex assembly
8	0000387	biological_process	spliceosomal snRNP assembly
8	0000389	biological_process	mRNA 3'-splice site recognition
8	0000398	biological_process	mRNA splicing, via spliceosome
8	0003676	molecular_function	nucleic acid binding
8	0003723	molecular_function	RNA binding
8	0005515	molecular_function	protein binding
8	0005634	cellular_component	nucleus
8	0005654	cellular_component	nucleoplasm
8	0005681	cellular_component	spliceosomal complex
8	0005684	cellular_component	U2-type spliceosomal complex
8	0005686	cellular_component	U2 snRNP
8	0006397	biological_process	mRNA processing
8	0008270	molecular_function	zinc ion binding
8	0008380	biological_process	RNA splicing
8	0010976	biological_process	positive regulation of neuron projection development
8	0016607	cellular_component	nuclear speck
8	0046872	molecular_function	metal ion binding
8	0071004	cellular_component	U2-type prespliceosome
8	0071005	cellular_component	U2-type precatalytic spliceosome
8	0071013	cellular_component	catalytic step 2 spliceosome
8	1903241	biological_process	U2-type prespliceosome assembly
9	0000375	biological_process	RNA splicing, via transesterification reactions
9	0000387	biological_process	spliceosomal snRNP assembly
9	0000389	biological_process	mRNA 3'-splice site recognition
9	0000398	biological_process	mRNA splicing, via spliceosome
9	0003676	molecular_function	nucleic acid binding
9	0003723	molecular_function	RNA binding
9	0005515	molecular_function	protein binding
9	0005634	cellular_component	nucleus
9	0005654	cellular_component	nucleoplasm
9	0005681	cellular_component	spliceosomal complex
9	0005684	cellular_component	U2-type spliceosomal complex
9	0005686	cellular_component	U2 snRNP
9	0006397	biological_process	mRNA processing
9	0008270	molecular_function	zinc ion binding
9	0008380	biological_process	RNA splicing
9	0016607	cellular_component	nuclear speck
9	0046872	molecular_function	metal ion binding
9	0071005	cellular_component	U2-type precatalytic spliceosome
9	0071013	cellular_component	catalytic step 2 spliceosome
9	1903241	biological_process	U2-type prespliceosome assembly
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000375	biological_process	RNA splicing, via transesterification reactions
A	0000387	biological_process	spliceosomal snRNP assembly
A	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0006397	biological_process	mRNA processing
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008380	biological_process	RNA splicing
A	0016020	cellular_component	membrane
A	0016607	cellular_component	nuclear speck
A	0017070	molecular_function	U6 snRNA binding
A	0030532	cellular_component	small nuclear ribonucleoprotein complex
A	0030619	molecular_function	U1 snRNA binding
A	0030620	molecular_function	U2 snRNA binding
A	0030623	molecular_function	U5 snRNA binding
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
A	0070530	molecular_function	K63-linked polyubiquitin modification-dependent protein binding
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071006	cellular_component	U2-type catalytic step 1 spliceosome
A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0071222	biological_process	cellular response to lipopolysaccharide
A	0071356	biological_process	cellular response to tumor necrosis factor
A	0097157	molecular_function	pre-mRNA intronic binding
A	0140492	molecular_function	metal-dependent deubiquitinase activity
A	1990904	cellular_component	ribonucleoprotein complex
B	0000166	molecular_function	nucleotide binding
B	0000244	biological_process	spliceosomal tri-snRNP complex assembly
B	0000354	biological_process	cis assembly of pre-catalytic spliceosome
B	0000387	biological_process	spliceosomal snRNP assembly
B	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0001649	biological_process	osteoblast differentiation
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0003724	molecular_function	RNA helicase activity
B	0004386	molecular_function	helicase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005681	cellular_component	spliceosomal complex
B	0005682	cellular_component	U5 snRNP
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0030532	cellular_component	small nuclear ribonucleoprotein complex
B	0042802	molecular_function	identical protein binding
B	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
B	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
B	0071005	cellular_component	U2-type precatalytic spliceosome
B	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B	0071013	cellular_component	catalytic step 2 spliceosome
B1	0000245	biological_process	spliceosomal complex assembly
B1	0000375	biological_process	RNA splicing, via transesterification reactions
B1	0000387	biological_process	spliceosomal snRNP assembly
B1	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B1	0000398	biological_process	mRNA splicing, via spliceosome
B1	0000785	cellular_component	chromatin
B1	0003723	molecular_function	RNA binding
B1	0003729	molecular_function	mRNA binding
B1	0005515	molecular_function	protein binding
B1	0005634	cellular_component	nucleus
B1	0005654	cellular_component	nucleoplasm
B1	0005681	cellular_component	spliceosomal complex
B1	0005684	cellular_component	U2-type spliceosomal complex
B1	0005686	cellular_component	U2 snRNP
B1	0005689	cellular_component	U12-type spliceosomal complex
B1	0005730	cellular_component	nucleolus
B1	0006338	biological_process	chromatin remodeling
B1	0006397	biological_process	mRNA processing
B1	0008380	biological_process	RNA splicing
B1	0016607	cellular_component	nuclear speck
B1	0031981	cellular_component	nuclear lumen
B1	0034693	cellular_component	U11/U12 snRNP
B1	0036002	molecular_function	pre-mRNA binding
B1	0045943	biological_process	positive regulation of transcription by RNA polymerase I
B1	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B1	0045945	biological_process	positive regulation of transcription by RNA polymerase III
B1	0071004	cellular_component	U2-type prespliceosome
B1	0071005	cellular_component	U2-type precatalytic spliceosome
B1	0071013	cellular_component	catalytic step 2 spliceosome
B1	1903241	biological_process	U2-type prespliceosome assembly
B1	1990935	molecular_function	splicing factor binding
B2	0000387	biological_process	spliceosomal snRNP assembly
B2	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B2	0000398	biological_process	mRNA splicing, via spliceosome
B2	0003723	molecular_function	RNA binding
B2	0005515	molecular_function	protein binding
B2	0005634	cellular_component	nucleus
B2	0005654	cellular_component	nucleoplasm
B2	0005681	cellular_component	spliceosomal complex
B2	0005684	cellular_component	U2-type spliceosomal complex
B2	0005686	cellular_component	U2 snRNP
B2	0005689	cellular_component	U12-type spliceosomal complex
B2	0006397	biological_process	mRNA processing
B2	0008380	biological_process	RNA splicing
B2	0016607	cellular_component	nuclear speck
B2	0071005	cellular_component	U2-type precatalytic spliceosome
B2	0071011	cellular_component	precatalytic spliceosome
B2	0071013	cellular_component	catalytic step 2 spliceosome
B2	1903241	biological_process	U2-type prespliceosome assembly
B3	0000375	biological_process	RNA splicing, via transesterification reactions
B3	0000387	biological_process	spliceosomal snRNP assembly
B3	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B3	0000398	biological_process	mRNA splicing, via spliceosome
B3	0003676	molecular_function	nucleic acid binding
B3	0005515	molecular_function	protein binding
B3	0005634	cellular_component	nucleus
B3	0005654	cellular_component	nucleoplasm
B3	0005681	cellular_component	spliceosomal complex
B3	0005684	cellular_component	U2-type spliceosomal complex
B3	0005686	cellular_component	U2 snRNP
B3	0005689	cellular_component	U12-type spliceosomal complex
B3	0005730	cellular_component	nucleolus
B3	0006282	biological_process	regulation of DNA repair
B3	0006397	biological_process	mRNA processing
B3	0008380	biological_process	RNA splicing
B3	0030620	molecular_function	U2 snRNA binding
B3	0042177	biological_process	negative regulation of protein catabolic process
B3	0043484	biological_process	regulation of RNA splicing
B3	0044877	molecular_function	protein-containing complex binding
B3	0045893	biological_process	positive regulation of DNA-templated transcription
B3	0071005	cellular_component	U2-type precatalytic spliceosome
B3	0071013	cellular_component	catalytic step 2 spliceosome
B3	1903241	biological_process	U2-type prespliceosome assembly
B4	0000375	biological_process	RNA splicing, via transesterification reactions
B4	0000387	biological_process	spliceosomal snRNP assembly
B4	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B4	0000398	biological_process	mRNA splicing, via spliceosome
B4	0003676	molecular_function	nucleic acid binding
B4	0003723	molecular_function	RNA binding
B4	0005515	molecular_function	protein binding
B4	0005634	cellular_component	nucleus
B4	0005654	cellular_component	nucleoplasm
B4	0005681	cellular_component	spliceosomal complex
B4	0005684	cellular_component	U2-type spliceosomal complex
B4	0005686	cellular_component	U2 snRNP
B4	0005689	cellular_component	U12-type spliceosomal complex
B4	0006397	biological_process	mRNA processing
B4	0008380	biological_process	RNA splicing
B4	0071005	cellular_component	U2-type precatalytic spliceosome
B4	0071011	cellular_component	precatalytic spliceosome
B4	1903241	biological_process	U2-type prespliceosome assembly
B4	1990935	molecular_function	splicing factor binding
B5	0000387	biological_process	spliceosomal snRNP assembly
B5	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B5	0000398	biological_process	mRNA splicing, via spliceosome
B5	0003723	molecular_function	RNA binding
B5	0005515	molecular_function	protein binding
B5	0005634	cellular_component	nucleus
B5	0005654	cellular_component	nucleoplasm
B5	0005681	cellular_component	spliceosomal complex
B5	0005684	cellular_component	U2-type spliceosomal complex
B5	0005686	cellular_component	U2 snRNP
B5	0005689	cellular_component	U12-type spliceosomal complex
B5	0006282	biological_process	regulation of DNA repair
B5	0006397	biological_process	mRNA processing
B5	0008380	biological_process	RNA splicing
B5	0043484	biological_process	regulation of RNA splicing
B5	0045893	biological_process	positive regulation of DNA-templated transcription
B5	0071005	cellular_component	U2-type precatalytic spliceosome
B5	0071011	cellular_component	precatalytic spliceosome
B5	1903241	biological_process	U2-type prespliceosome assembly
B5	1990935	molecular_function	splicing factor binding
B6	0000387	biological_process	spliceosomal snRNP assembly
B6	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B6	0000398	biological_process	mRNA splicing, via spliceosome
B6	0003676	molecular_function	nucleic acid binding
B6	0003723	molecular_function	RNA binding
B6	0003729	molecular_function	mRNA binding
B6	0005515	molecular_function	protein binding
B6	0005634	cellular_component	nucleus
B6	0005654	cellular_component	nucleoplasm
B6	0005681	cellular_component	spliceosomal complex
B6	0005684	cellular_component	U2-type spliceosomal complex
B6	0005689	cellular_component	U12-type spliceosomal complex
B6	0006397	biological_process	mRNA processing
B6	0008380	biological_process	RNA splicing
B6	1903241	biological_process	U2-type prespliceosome assembly
BP	0000387	biological_process	spliceosomal snRNP assembly
BP	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
BP	0000398	biological_process	mRNA splicing, via spliceosome
BP	0003677	molecular_function	DNA binding
BP	0003723	molecular_function	RNA binding
BP	0005515	molecular_function	protein binding
BP	0005634	cellular_component	nucleus
BP	0005654	cellular_component	nucleoplasm
BP	0005681	cellular_component	spliceosomal complex
BP	0005684	cellular_component	U2-type spliceosomal complex
BP	0005686	cellular_component	U2 snRNP
BP	0005689	cellular_component	U12-type spliceosomal complex
BP	0006351	biological_process	DNA-templated transcription
BP	0006397	biological_process	mRNA processing
BP	0008270	molecular_function	zinc ion binding
BP	0008380	biological_process	RNA splicing
BP	0016363	cellular_component	nuclear matrix
BP	0016607	cellular_component	nuclear speck
BP	0045893	biological_process	positive regulation of DNA-templated transcription
BP	0046872	molecular_function	metal ion binding
BP	0048863	biological_process	stem cell differentiation
BP	0071005	cellular_component	U2-type precatalytic spliceosome
BP	0071011	cellular_component	precatalytic spliceosome
BP	1903241	biological_process	U2-type prespliceosome assembly
C	0000166	molecular_function	nucleotide binding
C	0000244	biological_process	spliceosomal tri-snRNP complex assembly
C	0000387	biological_process	spliceosomal snRNP assembly
C	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003723	molecular_function	RNA binding
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005681	cellular_component	spliceosomal complex
C	0005829	cellular_component	cytosol
C	0006397	biological_process	mRNA processing
C	0008380	biological_process	RNA splicing
C	0015030	cellular_component	Cajal body
C	0016020	cellular_component	membrane
C	0016607	cellular_component	nuclear speck
C	0030623	molecular_function	U5 snRNA binding
C	0042220	biological_process	response to cocaine
C	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
C	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
C	0071005	cellular_component	U2-type precatalytic spliceosome
C	0071007	cellular_component	U2-type catalytic step 2 spliceosome
C	0071013	cellular_component	catalytic step 2 spliceosome
C	0071466	biological_process	cellular response to xenobiotic stimulus
D	0000245	biological_process	spliceosomal complex assembly
D	0000375	biological_process	RNA splicing, via transesterification reactions
D	0000387	biological_process	spliceosomal snRNP assembly
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005681	cellular_component	spliceosomal complex
D	0005682	cellular_component	U5 snRNP
D	0006397	biological_process	mRNA processing
D	0008380	biological_process	RNA splicing
D	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
D	0051301	biological_process	cell division
D	0071005	cellular_component	U2-type precatalytic spliceosome
E	0000244	biological_process	spliceosomal tri-snRNP complex assembly
E	0000375	biological_process	RNA splicing, via transesterification reactions
E	0000387	biological_process	spliceosomal snRNP assembly
E	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003723	molecular_function	RNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0005682	cellular_component	U5 snRNP
E	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
E	0006396	biological_process	RNA processing
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0016607	cellular_component	nuclear speck
E	0071007	cellular_component	U2-type catalytic step 2 spliceosome
E	0071013	cellular_component	catalytic step 2 spliceosome
F	0000244	biological_process	spliceosomal tri-snRNP complex assembly
F	0000245	biological_process	spliceosomal complex assembly
F	0000375	biological_process	RNA splicing, via transesterification reactions
F	0000387	biological_process	spliceosomal snRNP assembly
F	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005681	cellular_component	spliceosomal complex
F	0006396	biological_process	RNA processing
F	0006397	biological_process	mRNA processing
F	0008380	biological_process	RNA splicing
F	0015030	cellular_component	Cajal body
F	0016607	cellular_component	nuclear speck
F	0017070	molecular_function	U6 snRNA binding
F	0030621	molecular_function	U4 snRNA binding
F	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
F	0071001	cellular_component	U4/U6 snRNP
F	0071005	cellular_component	U2-type precatalytic spliceosome
F	0097525	cellular_component	spliceosomal snRNP complex
G	0000166	molecular_function	nucleotide binding
G	0000244	biological_process	spliceosomal tri-snRNP complex assembly
G	0000354	biological_process	cis assembly of pre-catalytic spliceosome
G	0000375	biological_process	RNA splicing, via transesterification reactions
G	0000387	biological_process	spliceosomal snRNP assembly
G	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
G	0000398	biological_process	mRNA splicing, via spliceosome
G	0000785	cellular_component	chromatin
G	0003676	molecular_function	nucleic acid binding
G	0003723	molecular_function	RNA binding
G	0003724	molecular_function	RNA helicase activity
G	0003729	molecular_function	mRNA binding
G	0004386	molecular_function	helicase activity
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005681	cellular_component	spliceosomal complex
G	0005682	cellular_component	U5 snRNP
G	0005694	cellular_component	chromosome
G	0005730	cellular_component	nucleolus
G	0006397	biological_process	mRNA processing
G	0008380	biological_process	RNA splicing
G	0016787	molecular_function	hydrolase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
G	0062176	biological_process	R-loop processing
G	0070062	cellular_component	extracellular exosome
G	0071013	cellular_component	catalytic step 2 spliceosome
J	0000244	biological_process	spliceosomal tri-snRNP complex assembly
J	0000245	biological_process	spliceosomal complex assembly
J	0000375	biological_process	RNA splicing, via transesterification reactions
J	0000387	biological_process	spliceosomal snRNP assembly
J	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
J	0000398	biological_process	mRNA splicing, via spliceosome
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005681	cellular_component	spliceosomal complex
J	0006397	biological_process	mRNA processing
J	0008380	biological_process	RNA splicing
J	0015030	cellular_component	Cajal body
J	0016607	cellular_component	nuclear speck
J	0032991	cellular_component	protein-containing complex
J	0042802	molecular_function	identical protein binding
J	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
J	0071005	cellular_component	U2-type precatalytic spliceosome
L	0000244	biological_process	spliceosomal tri-snRNP complex assembly
L	0000387	biological_process	spliceosomal snRNP assembly
L	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005681	cellular_component	spliceosomal complex
L	0005684	cellular_component	U2-type spliceosomal complex
L	0005687	cellular_component	U4 snRNP
L	0005690	cellular_component	U4atac snRNP
L	0006397	biological_process	mRNA processing
L	0008380	biological_process	RNA splicing
L	0015030	cellular_component	Cajal body
L	0016607	cellular_component	nuclear speck
L	0030621	molecular_function	U4 snRNA binding
L	0030622	molecular_function	U4atac snRNA binding
L	0030674	molecular_function	protein-macromolecule adaptor activity
L	0042802	molecular_function	identical protein binding
L	0043021	molecular_function	ribonucleoprotein complex binding
L	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
L	0048254	biological_process	snoRNA localization
L	0070990	molecular_function	snRNP binding
L	0071005	cellular_component	U2-type precatalytic spliceosome
L	0071011	cellular_component	precatalytic spliceosome
L	0071166	biological_process	ribonucleoprotein complex localization
L	0071339	cellular_component	MLL1 complex
L	0097526	cellular_component	spliceosomal tri-snRNP complex
L	1990904	cellular_component	ribonucleoprotein complex
M	0000244	biological_process	spliceosomal tri-snRNP complex assembly
M	0000245	biological_process	spliceosomal complex assembly
M	0000387	biological_process	spliceosomal snRNP assembly
M	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
M	0000398	biological_process	mRNA splicing, via spliceosome
M	0000451	biological_process	rRNA 2'-O-methylation
M	0000492	biological_process	box C/D snoRNP assembly
M	0001651	cellular_component	dense fibrillar component
M	0003723	molecular_function	RNA binding
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005681	cellular_component	spliceosomal complex
M	0005690	cellular_component	U4atac snRNP
M	0005730	cellular_component	nucleolus
M	0006397	biological_process	mRNA processing
M	0008380	biological_process	RNA splicing
M	0016556	biological_process	mRNA modification
M	0030182	biological_process	neuron differentiation
M	0030490	biological_process	maturation of SSU-rRNA
M	0030515	molecular_function	snoRNA binding
M	0030621	molecular_function	U4 snRNA binding
M	0030622	molecular_function	U4atac snRNA binding
M	0031428	cellular_component	box C/D methylation guide snoRNP complex
M	0032040	cellular_component	small-subunit processome
M	0032991	cellular_component	protein-containing complex
M	0034511	molecular_function	U3 snoRNA binding
M	0034512	molecular_function	box C/D sno(s)RNA binding
M	0042254	biological_process	ribosome biogenesis
M	0042274	biological_process	ribosomal small subunit biogenesis
M	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
M	0051117	molecular_function	ATPase binding
M	0071005	cellular_component	U2-type precatalytic spliceosome
M	0071011	cellular_component	precatalytic spliceosome
M	1990904	cellular_component	ribonucleoprotein complex
N	0000244	biological_process	spliceosomal tri-snRNP complex assembly
N	0000245	biological_process	spliceosomal complex assembly
N	0000375	biological_process	RNA splicing, via transesterification reactions
N	0000387	biological_process	spliceosomal snRNP assembly
N	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
N	0000398	biological_process	mRNA splicing, via spliceosome
N	0003723	molecular_function	RNA binding
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005681	cellular_component	spliceosomal complex
N	0005682	cellular_component	U5 snRNP
N	0006396	biological_process	RNA processing
N	0006397	biological_process	mRNA processing
N	0006403	biological_process	RNA localization
N	0008380	biological_process	RNA splicing
N	0016020	cellular_component	membrane
N	0016607	cellular_component	nuclear speck
N	0030674	molecular_function	protein-macromolecule adaptor activity
N	0042802	molecular_function	identical protein binding
N	0043021	molecular_function	ribonucleoprotein complex binding
N	0045944	biological_process	positive regulation of transcription by RNA polymerase II
N	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
N	0071005	cellular_component	U2-type precatalytic spliceosome
N	0071013	cellular_component	catalytic step 2 spliceosome
S	0000244	biological_process	spliceosomal tri-snRNP complex assembly
S	0000387	biological_process	spliceosomal snRNP assembly
S	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
S	0000398	biological_process	mRNA splicing, via spliceosome
S	0000481	biological_process	maturation of 5S rRNA
S	0003723	molecular_function	RNA binding
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005681	cellular_component	spliceosomal complex
S	0005737	cellular_component	cytoplasm
S	0005794	cellular_component	Golgi apparatus
S	0005829	cellular_component	cytosol
S	0006397	biological_process	mRNA processing
S	0008380	biological_process	RNA splicing
S	0015030	cellular_component	Cajal body
S	0016607	cellular_component	nuclear speck
S	0045292	biological_process	mRNA cis splicing, via spliceosome
S	0045585	biological_process	positive regulation of cytotoxic T cell differentiation
S	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
S	0071005	cellular_component	U2-type precatalytic spliceosome
S	0071013	cellular_component	catalytic step 2 spliceosome
U	0000244	biological_process	spliceosomal tri-snRNP complex assembly
U	0000245	biological_process	spliceosomal complex assembly
U	0000387	biological_process	spliceosomal snRNP assembly
U	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
U	0000398	biological_process	mRNA splicing, via spliceosome
U	0004843	molecular_function	cysteine-type deubiquitinase activity
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005681	cellular_component	spliceosomal complex
U	0006397	biological_process	mRNA processing
U	0008270	molecular_function	zinc ion binding
U	0008380	biological_process	RNA splicing
U	0016579	biological_process	protein deubiquitination
U	0016787	molecular_function	hydrolase activity
U	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
U	0046872	molecular_function	metal ion binding
U	0051301	biological_process	cell division
W	0000398	biological_process	mRNA splicing, via spliceosome
W	0000413	biological_process	protein peptidyl-prolyl isomerization
W	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
W	0005515	molecular_function	protein binding
W	0005654	cellular_component	nucleoplasm
W	0005681	cellular_component	spliceosomal complex
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0006397	biological_process	mRNA processing
W	0006457	biological_process	protein folding
W	0008380	biological_process	RNA splicing
W	0016018	molecular_function	cyclosporin A binding
W	0016607	cellular_component	nuclear speck
W	0016853	molecular_function	isomerase activity
W	0043021	molecular_function	ribonucleoprotein complex binding
W	0045070	biological_process	positive regulation of viral genome replication
W	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
W	0065003	biological_process	protein-containing complex assembly
W	0071001	cellular_component	U4/U6 snRNP

Functional Information from PROSITE/UniProt

site_id	PS00039
Number of Residues	9
Details	DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VLDEADRmI

Chain	Residue	Details
G	VAL547-ILE555

---

site_id	PS00170
Number of Residues	18
Details	CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YkgStFHRVIkdFMiQGG

Chain	Residue	Details
W	TYR60-GLY77

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FVCSATH

Chain	Residue	Details
B3	PHE287-HIS293

---

site_id	PS00436
Number of Residues	12
Details	PEROXIDASE_2 Peroxidases active site signature. TVrvARVmWHPS

Chain	Residue	Details
F	THR323-SER334

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LGTTcyDrSWRLWDL

Chain	Residue	Details
F	LEU338-LEU352
F	ILE422-LEU436
E	LEU81-VAL95
E	LEU124-SER138
E	VAL167-ILE181
E	ILE208-LEU222
E	ILE300-THR314

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CedknVPYvfVrSKqaLG

Chain	Residue	Details
M	CYS73-GLY90

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1039
Details	Domain: {"description":"Sm","evidences":[{"source":"PROSITE-ProRule","id":"PRU01346","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17525332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N-acetylthreonine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2005","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V."]}},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	78
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	86
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	79
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	78
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	78
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	79
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	63
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	61
Details	Zinc finger: {"description":"Matrin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00130","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	11
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	4
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"source":"PubMed","id":"21349847","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	11
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2004","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Modified residue: {"description":"Symmetric dimethylarginine; by PRMT9; alternate","evidences":[{"source":"PubMed","id":"25737013","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	11
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	77
Details	Region: {"description":"Interaction with SF3B1 and SF3B3","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	7
Details	Site: {"description":"Interaction with RNA","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	37
Details	Region: {"description":"Interaction with PHF5A, SF3B1 and SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	56
Details	Region: {"description":"Interaction with SF3B1 and SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	21
Details	Region: {"description":"Interaction with SF3B1","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	23
Details	Region: {"description":"Interaction with SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	5
Details	Site: {"description":"Interaction with SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	2
Details	Site: {"description":"Interaction with SF3B1","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	3
Details	Region: {"description":"Interaction with SF3B3","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28541300","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IFE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5SYB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	4
Details	Site: {"description":"Interaction with SF3B3","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"P83870","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	39
Details	Repeat: {"description":"HEAT 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	34
Details	Repeat: {"description":"HEAT 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	37
Details	Repeat: {"description":"HEAT 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	34
Details	Repeat: {"description":"HEAT 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	38
Details	Repeat: {"description":"HEAT 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	38
Details	Repeat: {"description":"HEAT 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	38
Details	Repeat: {"description":"HEAT 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	38
Details	Repeat: {"description":"HEAT 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	38
Details	Repeat: {"description":"HEAT 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	38
Details	Repeat: {"description":"HEAT 10"}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	38
Details	Repeat: {"description":"HEAT 11"}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	39
Details	Region: {"description":"Interaction with SF3B14"}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	4
Details	Region: {"description":"Interaction with PHF5A","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	56
Details	Region: {"description":"Interaction with SF3B3 and SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	1
Details	Site: {"description":"Interaction with PHF5A","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	75
Details	Domain: {"description":"RRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	13
Details	Region: {"description":"Interaction with pre-mRNA branch site"}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	79
Details	Domain: {"description":"RRM 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Lilla S.","von Kriegsheim A.","Lempens A.","Kolch W."]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI60
Number of Residues	158
Details	Region: {"description":"Sufficient for interaction with CLNS1A","evidences":[{"source":"PubMed","id":"11747828","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI61
Number of Residues	21
Details	Repeat: {"description":"LRR 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI62
Number of Residues	21
Details	Repeat: {"description":"LRR 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI63
Number of Residues	21
Details	Repeat: {"description":"LRR 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI64
Number of Residues	21
Details	Repeat: {"description":"LRR 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI65
Number of Residues	38
Details	Domain: {"description":"LRRCT"}

Chain

Residue

Details

---

site_id	SWS_FT_FI66
Number of Residues	183
Details	Domain: {"description":"Helicase ATP-binding 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI67
Number of Residues	237
Details	Domain: {"description":"Helicase C-terminal 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI68
Number of Residues	305
Details	Domain: {"description":"SEC63 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI69
Number of Residues	175
Details	Domain: {"description":"Helicase ATP-binding 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI70
Number of Residues	208
Details	Domain: {"description":"Helicase C-terminal 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI71
Number of Residues	312
Details	Domain: {"description":"SEC63 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI72
Number of Residues	3
Details	Motif: {"description":"DEIH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI73
Number of Residues	3
Details	Motif: {"description":"DEVH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI74
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23045696","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4F93","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI75
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"F1LNJ2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI76
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q6P4T2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI77
Number of Residues	162
Details	Domain: {"description":"PPIase cyclophilin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00156","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI78
Number of Residues	330
Details	Domain: {"description":"USP"}

Chain

Residue

Details

---

site_id	SWS_FT_FI79
Number of Residues	97
Details	Zinc finger: {"description":"UBP-type; degenerate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00502","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI80
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00502","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI81
Number of Residues	205
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI82
Number of Residues	28
Details	Motif: {"description":"Q motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00552","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI83
Number of Residues	3
Details	Motif: {"description":"DEAD box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI84
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI85
Number of Residues	118
Details	Domain: {"description":"Nop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00690","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI86
Number of Residues	23
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI87
Number of Residues	34
Details	Coiled coil: {"evidences":[{"source":"PubMed","id":"17412961","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI88
Number of Residues	13
Details	Motif: {"description":"Nuclear localization signal (NLS)","evidences":[{"source":"PubMed","id":"12444105","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI89
Number of Residues	1
Details	Site: {"description":"Interaction with U4 snRNA","evidences":[{"source":"PubMed","id":"17412961","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI90
Number of Residues	3
Details	Site: {"description":"Interaction with U4 snRNA and U4atac snRNA","evidences":[{"source":"PubMed","id":"17412961","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI91
Number of Residues	1
Details	Site: {"description":"Interaction with U4atac snRNA","evidences":[{"source":"PubMed","id":"17412961","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI92
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI93
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI94
Number of Residues	32
Details	Repeat: {"description":"HAT 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI95
Number of Residues	26
Details	Repeat: {"description":"HAT 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI96
Number of Residues	31
Details	Repeat: {"description":"HAT 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI97
Number of Residues	32
Details	Repeat: {"description":"HAT 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI98
Number of Residues	32
Details	Repeat: {"description":"HAT 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI99
Number of Residues	32
Details	Repeat: {"description":"HAT 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI100
Number of Residues	32
Details	Repeat: {"description":"HAT 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI101
Number of Residues	32
Details	Repeat: {"description":"HAT 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI102
Number of Residues	32
Details	Repeat: {"description":"HAT 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI103
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI104
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI105
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI106
Number of Residues	131
Details	Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI107
Number of Residues	491
Details	Region: {"description":"Reverse transcriptase homology domain"}

Chain

Residue

Details

---

site_id	SWS_FT_FI108
Number of Residues	273
Details	Region: {"description":"Linker"}

Chain

Residue

Details

---

site_id	SWS_FT_FI109
Number of Residues	13
Details	Region: {"description":"Important for branch point selection","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI110
Number of Residues	171
Details	Region: {"description":"Restriction endonuclease homology domain"}

Chain

Residue

Details

---

site_id	SWS_FT_FI111
Number of Residues	253
Details	Region: {"description":"RNase H homology domain"}

Chain

Residue

Details

---

site_id	SWS_FT_FI112
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI113
Number of Residues	1
Details	Modified residue: {"description":"N6,N6-dimethyllysine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI114
Number of Residues	282
Details	Domain: {"description":"tr-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI115
Number of Residues	14
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI116
Number of Residues	12
Details	Region: {"description":"Interaction with U4 snRNA and U4atac snRNA","evidences":[{"source":"PubMed","id":"17412961","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21784869","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI117
Number of Residues	32
Details	Region: {"description":"Important for U4 snRNA-binding","evidences":[{"source":"PubMed","id":"10545122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI118
Number of Residues	2
Details	Site: {"description":"Interaction with U4 snRNA and U4atac snRNA","evidences":[{"source":"PubMed","id":"17412961","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21784869","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI119
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D0T1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI120
Number of Residues	42
Details	Repeat: {"description":"SURP motif 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI121
Number of Residues	1
Details	Site: {"description":"Critical for binding to SF3A3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI122
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI123
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---