8RHQ

Crystal structure of HLA-A*11:01 in complex with SVLNDIFSRL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)

8RHQ の概要

• エントリーDOI: 10.2210/pdb8rhq/pdb
• 分子名称: HLA class I histocompatibility antigen, Beta-2-microglobulin, Spike protein S2', ... (9 entities in total)
• 機能のキーワード: human leukocyte antigen, major histocompatibility complex, hla-a11, hla-a*11:01, sars-cov-2, spike, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 163449.16

構造登録者

Ahn, Y.M.,Maddumage, J.C.,Szeto, C.,Gras, S. (登録日: 2023-12-16, 公開日: 2024-05-15, 最終更新日: 2024-05-22)

• 主引用文献: Ahn, Y.M.,Maddumage, J.C.,Grant, E.J.,Chatzileontiadou, D.S.M.,Perera, W.W.J.G.,Baker, B.M.,Szeto, C.,Gras, S.; The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.; Curr Res Struct Biol, 7:100148-100148, 2024; PubMed: 38742159; DOI: 10.1016/j.crstbi.2024.100148

実験手法

X-RAY DIFFRACTION (2 Å)