8RHH

Microtubule-associated kinesin-1 tail complex bound to AMPPNP, two-headed state

This is a non-PDB format compatible entry.

Summary for 8RHH

• Entry DOI: 10.2210/pdb8rhh/pdb
• Related: 8RHB
• EMDB information: 19174 19176
• Descriptor: Tubulin beta chain, Kinesin-1 heavy chain, Tubulin alpha-1B chain, ... (8 entities in total)
• Functional Keywords: kinesin autoinhibition motor microtubules mechanochemistry intracellular transport, motor protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 542442.22

Authors

Atherton, J.,Chegkazi, M.S.,Steiner, R.A. (deposition date: 2023-12-15, release date: 2024-11-20)

• Primary citation: Atherton, J.,Chegkazi, M.S.,Peirano, E.,Pozzer, L.S.,Foran, T.,Steiner, R.A.; Microtubule association induces a Mg-free apo-like ADP pre-release conformation in kinesin-1 that is unaffected by its autoinhibitory tail; Biorxiv, 2024; DOI: 10.1101/2024.11.11.622991

Experimental method

ELECTRON MICROSCOPY (3 Å)