8RF3
Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 7G3 refined against the anomalous diffraction data
This is a non-PDB format compatible entry.
Summary for 8RF3
Entry DOI | 10.2210/pdb8rf3/pdb |
Descriptor | Host translation inhibitor nsp1, 2-(1-benzothiophen-3-yl)ethanoic acid (3 entities in total) |
Functional Keywords | viral protein, sars-cov-2, non-structural protein 1, nsp1, fragment hit, anomalous diffraction, protein binding |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 1 |
Total formula weight | 13301.39 |
Authors | Ma, S.,Damfo, S.,Mykhaylyk, V.,Kozielski, F. (deposition date: 2023-12-12, release date: 2024-06-19) |
Primary citation | Ma, S.,Damfo, S.,Bowler, M.W.,Mykhaylyk, V.,Kozielski, F. High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms. Acta Crystallogr D Struct Biol, 80:451-463, 2024 Cited by PubMed: 38841886DOI: 10.1107/S2059798324004480 PDB entries with the same primary citation |
Experimental method |
Structure validation
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