8RDI

Crystal structure of UDP-galactose 4-epimerase from Pyrococcus horikoshii containing Y145F mutation and with bound NAD and GDP-L-fucose

8RDI の概要

• エントリーDOI: 10.2210/pdb8rdi/pdb
• 分子名称: SDR family NAD(P)-dependent oxidoreductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE (3 entities in total)
• 機能のキーワード: udp-galactose 4-epimerase, gale, rossmann fold, gdp-l-fucose, isomerase
• 由来する生物種: Pyrococcus horikoshii
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 151794.24

構造登録者

Thunnissen, A.M.W.H.,Alvarez Quispe, C.,Desmet, T. (登録日: 2023-12-08, 公開日: 2024-12-18)

• 主引用文献: Alvarez Quispe, C.,Savino, S.,Biarnes, X.,Planas, A.,Thunnissen, A.M.W.H.,Beerens, K.,Desmet, T.; Structural, computational and biochemical analysis reveal new insights in the specificity of a promiscuous GDP-Gal4E; To Be Published,

実験手法

X-RAY DIFFRACTION (3.1 Å)