8RD7
HUWE1 WWE domain in complex with ADP-ribose
Summary for 8RD7
Entry DOI | 10.2210/pdb8rd7/pdb |
Descriptor | E3 ubiquitin-protein ligase HUWE1, CHLORIDE ION, ACETATE ION, ... (6 entities in total) |
Functional Keywords | e3 ligase, complex, nucleotide, ligase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 42965.97 |
Authors | Muenzker, L.,Zak, K.M.,Boettcher, J. (deposition date: 2023-12-07, release date: 2024-07-31, Last modification date: 2024-08-07) |
Primary citation | Munzker, L.,Kimani, S.W.,Fowkes, M.M.,Dong, A.,Zheng, H.,Li, Y.,Dasovich, M.,Zak, K.M.,Leung, A.K.L.,Elkins, J.M.,Kessler, D.,Arrowsmith, C.H.,Halabelian, L.,Bottcher, J. A ligand discovery toolbox for the WWE domain family of human E3 ligases. Commun Biol, 7:901-901, 2024 Cited by PubMed: 39048679DOI: 10.1038/s42003-024-06584-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.31 Å) |
Structure validation
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