8RB2

The crystal structure of DNA-bound human MutSbeta (MSH2_E749A/MSH3_E976A) in the canonical mismatch bound conformation with ADP bound in MSH2

8RB2 の概要

• エントリーDOI: 10.2210/pdb8rb2/pdb
• 分子名称: DNA mismatch repair protein Msh2, GLYCEROL, DNA mismatch repair protein Msh3, ... (11 entities in total)
• 機能のキーワード: dna repair, dna binding, dna binding protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 497141.59

構造登録者

Thomsen, M.,Neudegger, T.,Thieulin-Pardo, G.,Blaesse, M.,Costanzi, E.,Steinbacher, S.,Plotnikov, N.V.,Dominguez, C.,Iyer, R.R.,Wilkinson, H.A.,Monteagudo, E.,Haque, T.S.,Prasad, B.C.,Finley, M.,Boudet, J.,Vogt, T.F.,Felsenfeld, D.P. (登録日: 2023-12-01, 公開日: 2025-06-11, 最終更新日: 2025-07-09)

• 主引用文献: Thomsen, M.,Neudegger, T.,Thieulin-Pardo, G.,Blaesse, M.,Costanzi, E.,Steinbacher, S.,Plotnikov, N.V.,Dominguez, C.,Iyer, R.R.,Wilkinson, H.A.,Monteagudo, E.,Haque, T.S.,Prasad, B.C.,Finley, M.,Boudet, J.,Vogt, T.F.,Felsenfeld, D.P.; The crystal structure of DNA-bound human MutSbeta (MSH2/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3; To Be Published,

実験手法

X-RAY DIFFRACTION (2.526 Å)