8R8R
Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc)
Summary for 8R8R
Entry DOI | 10.2210/pdb8r8r/pdb |
EMDB information | 19008 |
Descriptor | Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33, Cleavage and polyadenylation specificity factor subunit 4, ... (6 entities in total) |
Functional Keywords | 3-end processing, polyadenylation, papoa, pre-mrna, cleavage and polyadenylation, rna binding protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 245363.66 |
Authors | Todesca, S.,Sandmeir, F.,Keidel, A.,Conti, E. (deposition date: 2023-11-29, release date: 2024-04-10) |
Primary citation | Todesca, S.,Sandmeir, F.,Keidel, A.,Conti, E. Molecular basis of human polyA polymerase recruitment by mPSF. Rna, 2024 Cited by PubMed: 38538052DOI: 10.1261/rna.079915.123 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.79 Å) |
Structure validation
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