8R8Q

Lysosomal peptide transporter

8R8Q の概要

• エントリーDOI: 10.2210/pdb8r8q/pdb
• EMDBエントリー: 19006
• 分子名称: Major facilitator superfamily domain-containing protein 1, Glycosylated lysosomal membrane protein, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: mfs transporter, mfsd family, nutrition transporter, lysosomal transporter, outward open, membrane protein
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 99974.30

構造登録者

Jungnickel, K.E.J.,Loew, C. (登録日: 2023-11-29, 公開日: 2024-05-01, 最終更新日: 2024-06-12)

• 主引用文献: Jungnickel, K.E.J.,Guelle, O.,Iguchi, M.,Dong, W.,Kotov, V.,Gabriel, F.,Debacker, C.,Dairou, J.,McCort-Tranchepain, I.,Laqtom, N.N.,Chan, S.H.,Ejima, A.,Sato, K.,Massa Lopez, D.,Saftig, P.,Mehdipour, A.R.,Abu-Remaileh, M.,Gasnier, B.,Low, C.,Damme, M.; MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes; Nature Cell Biology, 2024; DOI: 10.1038/s41556-024-01436-5

実験手法

ELECTRON MICROSCOPY (4.08 Å)