8R6B

DTX1 WWE domain in complex with ADP bound to WWE2

Summary for 8R6B

• Entry DOI: 10.2210/pdb8r6b/pdb
• Related: 8R5N
• Descriptor: E3 ubiquitin-protein ligase DTX1, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: e3 ligase, nucleotide, wwe domain, adp, ligase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 19827.22

Authors

Muenzker, L.,Zak, K.M.,Boettcher, J. (deposition date: 2023-11-21, release date: 2024-07-31, Last modification date: 2024-08-07)

• Primary citation: Munzker, L.,Kimani, S.W.,Fowkes, M.M.,Dong, A.,Zheng, H.,Li, Y.,Dasovich, M.,Zak, K.M.,Leung, A.K.L.,Elkins, J.M.,Kessler, D.,Arrowsmith, C.H.,Halabelian, L.,Bottcher, J.; A ligand discovery toolbox for the WWE domain family of human E3 ligases.; Commun Biol, 7:901-901, 2024; PubMed: 39048679; DOI: 10.1038/s42003-024-06584-w

Experimental method

X-RAY DIFFRACTION (2.5 Å)