8R5V

Crystal structure of bovine pancreatic ribonuclease A in complex with [Sp-PS]-mU-dT dinucleotide

Summary for 8R5V

• Entry DOI: 10.2210/pdb8r5v/pdb
• Descriptor: Ribonuclease pancreatic, 1-[(2~{R},4~{S},5~{R})-5-[[[(2~{R},6~{S})-2-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-6-(hydroxymethyl)morpholin-4-yl]-oxidanyl-phosphinothioyl]oxymethyl]-4-oxidanyl-oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione, DICHLORO-ACETIC ACID, ... (4 entities in total)
• Functional Keywords: complex, dinucleotide, inhibitor, ribonuclease, rnase, hydrolase
• Biological source: Bos taurus (cattle)
• Total number of polymer chains: 2
• Total formula weight: 33767.15

Authors

Dolot, R.,Jastrzebska, K.,Antonczyk, P. (deposition date: 2023-11-17, release date: 2023-12-06)

• Primary citation: Jastrzebska, K.,Antonczyk, P.,Dolot, R.; Synthesis of P-stereodefined morpholino dinucleoside-3',6'-thiophosphoramidates using unexpected activator.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)