8R5V

Crystal structure of bovine pancreatic ribonuclease A in complex with [Sp-PS]-mU-dT dinucleotide

8R5V の概要

• エントリーDOI: 10.2210/pdb8r5v/pdb
• 分子名称: Ribonuclease pancreatic, 1-[(2~{R},4~{S},5~{R})-5-[[[(2~{R},6~{S})-2-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-6-(hydroxymethyl)morpholin-4-yl]-oxidanyl-phosphinothioyl]oxymethyl]-4-oxidanyl-oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione, DICHLORO-ACETIC ACID, ... (4 entities in total)
• 機能のキーワード: complex, dinucleotide, inhibitor, ribonuclease, rnase, hydrolase
• 由来する生物種: Bos taurus (cattle)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 33767.15

構造登録者

Dolot, R.,Jastrzebska, K.,Antonczyk, P. (登録日: 2023-11-17, 公開日: 2023-12-06)

• 主引用文献: Jastrzebska, K.,Antonczyk, P.,Dolot, R.; Synthesis of P-stereodefined morpholino dinucleoside-3',6'-thiophosphoramidates using unexpected activator.; To Be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)