8R5K

The Fk1 domain of FKBP51 in complex with Antascomicine B

Summary for 8R5K

• Entry DOI: 10.2210/pdb8r5k/pdb
• Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP5, Antascomicine B (3 entities in total)
• Functional Keywords: isomerase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 14701.93

Authors

Voll, M.A.,Bracher, A.,Hausch, F. (deposition date: 2023-11-16, release date: 2024-05-08)

• Primary citation: Schafer, S.C.,Voll, A.M.,Bracher, A.,Ley, S.V.,Hausch, F.; Antascomicin B stabilizes FKBP51-Akt1 complexes as a molecular glue.; Bioorg.Med.Chem.Lett., 104:129728-129728, 2024; PubMed: 38582133; DOI: 10.1016/j.bmcl.2024.129728

Experimental method

X-RAY DIFFRACTION (0.89 Å)