8R5F

ERK2 covalently bound to RU83 cyclohexenone based inhibitor

Summary for 8R5F

• Entry DOI: 10.2210/pdb8r5f/pdb
• Descriptor: Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, GLYCEROL, ... (5 entities in total)
• Functional Keywords: mapk, map kinase, kinase, inhibitor, covalent inhibitor, signaling protein, erk2, mitogen-activated protein kinase 1
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 42639.57

Authors

Sok, P.,Poti, A.,Remenyi, A. (deposition date: 2023-11-16, release date: 2024-11-27)

• Primary citation: Poti, A.,Sok, P.,Remenyi, A.; The covalent coordination of cyclohexenone inhibitors in the MAP kinase docking groove; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)