8R3I

Proof of concept study of a probe molecule in TbPTR1

Summary for 8R3I

• Entry DOI: 10.2210/pdb8r3i/pdb
• Descriptor: Pteridine reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ~{N}-[(2~{R})-1-[4-[[2,4-bis(azanyl)quinazolin-5-yl]oxymethyl]piperidin-1-yl]-1-oxidanylidene-pent-4-yn-2-yl]ethanamide, ... (5 entities in total)
• Functional Keywords: pteridine reductase, trypanosomatids, short-chain dehydrogenase/reductase, oxidoreductase
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 4
• Total formula weight: 125476.27

Authors

Dawson, A.,GIlbert, I.H.,Montagna, S. (deposition date: 2023-11-09, release date: 2024-11-20)

• Primary citation: Montagna, S.,Gilbert, I.H.,Dawson, A.; Proof of concept study of a probe molecule in TbPTR1; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)