8R36

Crystal structure of the Gluk1 ligand-binding domain in complex with kainate and BPAM538 at 1.90 A resolution

8R36 の概要

• エントリーDOI: 10.2210/pdb8r36/pdb
• 分子名称: Glutamate receptor ionotropic, kainate 1, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, SULFATE ION, ... (7 entities in total)
• 機能のキーワード: ionotropic glutamate receptor, gluk1 ligand-binding domain, membrane protein, positive allosteric modulator, kainate
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60026.02

構造登録者

Bay, Y.,Frantsen, S.M.,Frydenvang, K.,Kastrup, J.S. (登録日: 2023-11-08, 公開日: 2024-08-14, 最終更新日: 2024-09-04)

• 主引用文献: Bay, Y.,Cabello, F.J.M.,Koens, C.C.,Frantsen, S.M.,Pickering, D.S.,Frydenvang, K.,Francotte, P.,Pirotte, B.,Kristensen, A.S.,Bowie, D.,Kastrup, J.S.; Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538.; J.Struct.Biol., 216:108113-108113, 2024; PubMed: 39079583; DOI: 10.1016/j.jsb.2024.108113

実験手法

X-RAY DIFFRACTION (1.9 Å)