8R1J
Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B.
Summary for 8R1J
| Entry DOI | 10.2210/pdb8r1j/pdb |
| EMDB information | 18818 |
| Descriptor | Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (4 entities in total) |
| Functional Keywords | influenza virus, replication platform, h5n1, influenza adaptive mutations, host adaptation, viral polymerase, cryo-em, hpai., viral protein |
| Biological source | Influenza A virus More |
| Total number of polymer chains | 7 |
| Total formula weight | 570009.87 |
| Authors | Carrique, L.,Staller, E.,Keown, J.R.,Fan, H.,Fodor, E.,Grimes, J.M. (deposition date: 2023-11-02, release date: 2024-05-08, Last modification date: 2024-05-29) |
| Primary citation | Staller, E.,Carrique, L.,Swann, O.C.,Fan, H.,Keown, J.R.,Sheppard, C.M.,Barclay, W.S.,Grimes, J.M.,Fodor, E. Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation. Nat Commun, 15:4123-4123, 2024 Cited by PubMed: 38750014DOI: 10.1038/s41467-024-48470-3 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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