8QZR

SARS-CoV-2 delta RBD complexed with BA.4/5-9 Fab

Summary for 8QZR

• Entry DOI: 10.2210/pdb8qzr/pdb
• Related: 8CBD 8CBE 8CMA
• Descriptor: BA.4/5-9 light chain, BA.4/5-9 heavy chain, Spike protein S1, ... (5 entities in total)
• Functional Keywords: viral protein/immune system, sars-cov-2, rbd, ba.4/5 mabs, ba.4/5-9 mab, viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 141515.65

Authors

Zhou, D.,Ren, J.,Stuart, D.I. (deposition date: 2023-10-29, release date: 2024-04-03, Last modification date: 2024-05-08)

• Primary citation: Liu, C.,Das, R.,Dijokaite-Guraliuc, A.,Zhou, D.,Mentzer, A.J.,Supasa, P.,Selvaraj, M.,Duyvesteyn, H.M.E.,Ritter, T.G.,Temperton, N.,Klenerman, P.,Dunachie, S.J.,Paterson, N.G.,Williams, M.A.,Hall, D.R.,Fry, E.E.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R.; Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection.; Nat Commun, 15:3284-3284, 2024; PubMed: 38627386; DOI: 10.1038/s41467-024-47393-3

Experimental method

X-RAY DIFFRACTION (3.77 Å)