8QX2

Aplysia californica acetylcholine-binding protein in complex with with racemic spiroimine (+)/(-)-4

Summary for 8QX2

• Entry DOI: 10.2210/pdb8qx2/pdb
• Related: 8Q1M 8QTL
• Descriptor: Soluble acetylcholine receptor, Spiroimine (+)-4 R, ISOPROPYL ALCOHOL, ... (4 entities in total)
• Functional Keywords: achbp, complex, spiroimine, aplysia californica, choline-binding protein
• Biological source: Aplysia californica (California sea hare)
• Total number of polymer chains: 5
• Total formula weight: 124814.07

Authors

Sulzenbacher, G.,Bourne, Y.,Marchot, P. (deposition date: 2023-10-20, release date: 2024-04-03)

• Primary citation: Bourne, Y.,Sulzenbacher, G.,Chabaud, L.,Araoz, R.,Radic, Z.,Conrod, S.,Taylor, P.,Guillou, C.,Molgo, J.,Marchot, P.; The Cyclic Imine Core Common to the Marine Macrocyclic Toxins Is Sufficient to Dictate Nicotinic Acetylcholine Receptor Antagonism; Mar Drugs, 22:-, 2024; DOI: 10.3390/md22040149

Experimental method

X-RAY DIFFRACTION (2.1 Å)